Large animal internal medicine / 4th ed.

作者：  [edited by] Bradford P. Smith.

出版社：

简介：　　Large Animal Internal Medicine, 4th Edition features a problem-based approach with discussions of over 150 clinical signs. This is the first internal medicine reference that enables you to efficiently diagnose horses, cattle, sheep, and goats based on clinical observation and laboratory and diagnostic testing. With this user-friendly format, you can find essential information about specific diseases and reach a diagnosis by simply identifying the signs. 　　 　　 A unique problem-based approach with discussions of over 150 clinical signs and manifestations helps you quickly reach a diagnosis based on observations and laboratory tests. Causes of Presenting Signs boxes provide easy access to complete lists of common, less common, and uncommon diseases associated with manifestations or signs of disease. Complete lists of diseases associated with a given lab abnormality in Causes of Abnormal Laboratory Values boxes help you easily interpret abnormalities in clinical chemistry, hematology, blood proteins, and clotting tests. An expert team of over 180 authors contributing information in their areas of expertise ensures you are using the most accurate and up-to-date information available. Color plates accompanying Diseases of the Eye and Diseases of the Alimentary Tract enable you to visually recognize the clinical appearance of ophthalmologic conditions and alimentary tract disorders for quick and easy diagnosis and treatment. 　　 　　Six all-new chapters provide in-depth coverage of diagnostic testing, critical care and fluid therapy, biosecurity and infection control, and genetic disorders.　　

作者：  

出版社：

简介：The fourth edition of this leading text reflects the new direction and growth of the field of hematology as an academic and clinical discipline. Edited and written by practitioners who are the leaders of the field, the book covers both the basic scientific foundations of hematology and its clinical aspects. It provides practitioners with the most comprehensive, authoritative, up-to-date information in hematology. The table of contents has been thoroughly revised with many new chapters added, ref更多>>

作者：  

出版社：

简介：Traditionally, incorporating optimal drug-like properties into a structural lead was not considered by medicinal chemists to be their responsibility. Instead, medicinal chemists felt that the undesirable drug-like properties in their drug candidates would be fixed by preclinical development scientists. However, that view has changed in the past 5a?10 years, resulting in another significant paradigm shift in drug discovery. The most significant aspect of this latest paradigm shift is the recognition by medicinal chemists that the drug-like properties of structural hits, structural leads, and drug candidates are intrinsic properties of the molecules and that it is the responsibility of the medicinal chemist to optimize not only the pharmacological properties but also the drug-like properties of these molecules. Therefore, assessment of these drug-like properties is now done early in the drug discovery process on structural hits and structural leads as well as the design of screening libraries. Optimization of these drug-like properties is done through an iterative process in close collaboration with preclinical development scientists. This process is analogous to the process used by the medicinal chemist to characterize and optimize the pharmacological activity of their structural hits, leads and drug candidates. Recognizing these changes in the paradigm by which drugs are discovered, the American Association of Pharmaceutical Scientists (AAPS) has recently organized and sponsored two focused workshops in the area of profiling drug-like properties during drug discovery. The first workshop, entitled "Pharmaceutical Profiling in Drug Discovery for Lead Selection", took place in Whippany, NJ on May 19-21, 2003. This workshop, which was co-sponsored by the American Chemical Society-Medicinal Chemistry Division and the Society for Biomolecular Screening, was focused on prediction, measurement, and utilization of drug-like properties during lead selection. From this workshop arose the book entitled Pharmaceutical Profiling in Drug discovery for Lead Selection, which was edited by Ronald T. Borchardt, Edward H. Kerns, Christopher A. Lipinski, Dhiren R. Thakker and Binghe Wang and published by AAPS Press (Arlington, VA) in 2004. The second workshop entitled "Optimizing the Drug-Like Properties of Leads in Drug Discovery" took place in Parsippany, NJ on September 19-22, 2004. This workshop, which was co-sponsored by the American Chemical Society-Medicinal Chemistry Division, American Chemical Society-North Jersey Section, American Society for Clinical Pharmacology and Therapeutics, European Federation for Pharmaceutical Sciences, International Society for the study of Xenobiotics, and the Society of Toxicology, was focused on the optimization of the drug-like properties of leads in drug discovery. If the strategies and the methodologies presented at this workshop were to be adopted by pharmaceutical and biotechnology companies, it is the belief of the workshopa's organizers that more higher quality drug candidates would be advancing into preclinical and clinical development resulting in more efficacious and safer drugs.

Upscaling and downscaling methods for environmental research /

作者：  edited by Marc F.P. Bierkens, Peter A. Finke and Peter de Willigen.

出版社：

简介：Environmental studies typically involve the combination of dynamic models with data sources at various spatial and temporal scales. Also, the scale of the model output is rarely in tune with the scale at which decision-makers require answers or implement environmental measures. Consequently, the question has been raised how to obtain results at the appropriate scale. Models, usually developed at the scale of a research project, have to be applied to larger areas (extrapolation), with incomplete data coverage (interpolation) and to different supports (upscaling and downscaling) to facilitate studies for decision-makers. This book gives an overview of the various problems involved, and focuses on a description of upscaling and downscaling methods that are known to exist. Furthermore, this book is the first in its kind in that it contains a decision support system that advises the practitioner on which upscaling or downscaling method to use in his specific context. This book is meant for an audience of MSc- and PhD-students, applied researchers and practitioners in soil science, hydrology, (agro) ecology, agronomy and the environmental sciences in general.

Principles of genetics / 3rd ed.

作者：  D. Peter Snustad, Michael J. Simmons ; epilogue by James F. Crow ; problems edited by H. James Pr...

出版社：

简介：出版日期: 2002年7月12日

作者：  

出版社：

简介：Summary: Publisher Summary 1 This reference provides experienced practitioners and those new to the field of health care fraud and abuse, with information on structuring acceptable business arrangements, defending clients, and implementing effective corporate compliance programs and other measures to reduce exposure under these complex laws. Some of the topics: the federal physician self-referral restrictions (the Stark Law), False Claims Act jurisprudence, hospital-physician relationships, managed care fraud and abuse risks, effective corporate compliance programs, practical considerations for defending health care fraud cases, and director and officer liabilities. The appendices provide reference materials on the anti-kickback statute, the Stark Law, the civil False Claims Act, the civil monetary penalty and exclusion provisions, private payer fraud, and numerous additional guidance materials including Special Fraud Alerts and Advisory Bulletins, the Self-Disclosure Protocol, and compliance program guidance documents. Supplements are issued annually. Edited by Baumann, member of a health care group in Washington D.C. Annotation c. Book News, Inc., Portland, OR (booknews.com)  

Pixelworld /

作者：  edited by Francis Lam, editor.

出版社：

简介：

作者：  

出版社：

简介：Summary: Publisher Summary 1 Comprises a comprehensive reference source that unifies the entire fields of atomic molecular and optical (AMO) physics, assembling the principal ideas, techniques and results of the field. 92 chapters written by about 120 authors present the principal ideas, techniques and results of the field, together with a guide to the primary research literature (carefully edited to ensure a uniform coverage and style, with extensive cross-references).Along with a summary of key ideas, techniques, and results, many chapters offer diagrams of apparatus, graphs, and tables of data. From atomic spectroscopy to applications in comets, one finds contributions from over 100 authors, all leaders in their respective disciplines. Substantially updated and expanded since the original 1996 edition, it now contains several entirely new chapters covering current areas of great research interest that barely existed in 1996, such as Bose-Einstein condensation, quantum information, and cosmological variations of the fundamental constants. A fully-searchable CD- ROM version of the contents accompanies the handbook.   Publisher Summary 2 This Springer Handbook comprises a comprehensive reference source that unifies the entire fields of atomic, molecular, and optical (AMO) physics, assembling the principal ideas, techniques, and results of the field. Its 90 chapters written by about 120 authors all leaders in their repsective disciplines, together with a guide to the primary research literature. It has been carefully edited to ensure a uniform coverage and style, with extensive cross-references. It is intended to be both a source of information and inspiration for graduate students and other researchers new to the field. Along with a summary of key ideas, techniques, and results, many chapters offer diagrams of apparatus, graphs, and tables of data. From atomic spectroscopy to applications in comets, one finds contributions from over 100 authors, all leaders in their respective disciplines. Substantially updated and expanded since the original 1996 edition, it now contains several entirely new chapters covering current areas of great research interest that barely existed in 1996, such as Bose-Einstein condensation, quantum information, and cosmological variations of the fundamental constants. A fully-searchable CD- ROM version of the contents accompanies the handbook.    

Designing East Asian FTA : rationale and feasibility /

作者：  edited by Zhang Yunling.

出版社：

简介：　　 　　 　　 《东亚自由贸易区的基础与可行性分析》内容简介：this is a research report on east asian fta (eafta) done bythe study group chaired by me. the research started from march of2004 and was jointly projected by institute of asia-pacific studies, chi-nese academy of social sciences (iaps, cass) and institute of de-veloping economies of japan external trade organization (ide-jetro). each side organized its own research team and conductedindependent study but with the close consultation and cooperation be-tween the two sides. 　　 　　

Medical cell biology = 图解医学细胞生物学 / 3rd ed.

作者：  edited by Steven R. Goodman.

出版社：

简介：

Africa, South and Southeast Asia /

作者：  edited by Rajend Mesthrie.

出版社：

简介：Designed for college courses in linguistics, this volume is part of an impressive four-volume set describing varieties of English worldwide. Each volume contains the tables of contents for all 4 volumes, and each begins with an introduction by the volume editor(s) to the geographical area discussed. The first part of each volume contains individual chapters on the phonology of the different varieties for the area--the 28 varieties of English in this volume include Cameroon, Nigerian Pidgin, Ghanaian, Ghanaian Pidgin, White South African, Black South African, and Pakistani. The second part is devoted to chapters on morphology and syntax for each variety. Each of the chapters is authored by a specialist in that variety of English and the CD-ROM contains interactive maps as well as speech samples. Also packaged as a four-volume set (ISBN: 978-3-11-017269-0). Annotation 漏2008 Book News, Inc., Portland, OR (booknews.com)

Handbook of plant nutrition /

作者：  edited by Allen V. Barker, David J. Pilbeam.

出版社：

简介：Handbook of Plant Nutrition explores the principles of plant nutrition from a historical standpoint to current knowledge of the requirements of crops for certain elements and the beneficial effects of others. This book presents historical background of each plant nutrient, demonstrating functions and essentiality of plants. With tabulated data used to correlate information to nutritional needs, it includes diagnosis of the nutritional status of plants through assessment of plant appearance and composition. It discusses the value of soil tests for evaluating the nutritional status of plants. The text also examines fertilizers that can be applied to remedy nutritional deficiencies in plants.

作者：  

出版社：

简介：The XV International Conference on Computational Methods in Water Resources (CMWR XV) was held in Chapel Hill, North Carolina, 13-17 June 2004. The conference was sponsored by the Department of Environmental Sciences and Engineering, School of Public Health, The University of North Carolina at Chapel Hill. This two-volume set represents the reviewed and edited proceedings of this meeting, including 156 papers. In addition, many posters were presented at the meeting, which are not included in this formal written record. These collective works include contributions by many of the leading water resources research groups from around the world. Broad in scope, these papers address numerous aspects of water resources systems, ranging from the microscale to the field scale and from the very fundamental to the most compelling and important of applications. Virtually all major classes of numerical methods for water resources problems are represented in these proceedings, from the evolution of traditional approaches to the latest in methods of recent invention. As has been traditional at past CMWR meetings, subsurface hydrology, land surface hydrology, and surface water hydrology are well represented.

作者：  

出版社：

简介：Summary: Publisher Summary 1 Because stem cells can grow and divide indefinitely and can also differentiate into specialized cell types, they promise significant advances in regenerative medicine. Recent work has led to the development of new methods for embryonic and adult stem cell isolation, characterization, expansion in undifferentiated state, customized differentiation, efficient stem cell transduction for gene therapy, quick monitoring of rejection, and other advances. This volume, edited by Vemuri (Invitrogen Corporation), presents a sample of methodological advances for wider use by novice and expert scientists, including derivation of human embryonic stem cells in xeno-free conditions, digital imaging of stem cells by electron microscopy, controlled-cooling protocol for cryopreservation of human and non-human primate embryonic stem cells, cell surface markers in human embryonic stem cells, generation of a monoclonal antibody library against human embryonic stem cells, gene transfer via nucleofection into adult and embryonic stem cells, isolation of stem cells from human umbilical cord blood in serum-free conditions, hematopoietic colony-forming cell assays, assays for alloreactive responses by polymerase chain reaction, adenoviral transduction of mesechymal stem cells, and 13 others. As in the rest of the series, each chapter describes laboratory protocols, necessary materials, troubleshooting, and known pitfalls. Annotation 漏2008 Book News, Inc., Portland, OR (booknews.com)   Publisher Summary 2 The scope for improving health care using stem cell therapies is thrilling, but has considerable technical challenges and methodological constraints that need to be addressed. Keeping with the tradition of Humana Press to bring these developments to the forefront in a timely manner, this book presents scientific advances in stem cell methods for a wider use by novice and expert scientists, through the series of Methods in Molecular Biology.  

作者：  

出版社：

简介：If you're looking for a book that will improve your knowledge and technical instruction skills in land, water, and snow and ice sports and activities, this is it! Technical Skills for Adventure Programming: A Curriculum Guide is an all-in-one resource, based on current methods, that will guide you in becoming a skilled adventure instructor in the classroom and in the field. This book includes -comprehensive units with lesson plans for 12 popular outdoor adventure activities; -7 to 15 progressive, pedagogically sound lesson plans for each unit, featuring foundational teaching methods, experiential learning activities, and assessment strategies for adventure technical skills; -a CD-ROM with printable lesson plans and supporting materials for each unit that make it easy to print only what you will need in the field; and -an overview of the teaching process as it relates to adventure-based activities, including discussions of adventure education theory, learning styles, experiential learning and teaching, and outdoor teaching tips and considerations. Edited by nationally known outdoor adventure educators, this book allows you to tap into the knowledge and expertise of skilled instructors who present progressive technical skills for these activities: -Backpacking -Canoeing -Caving -Ice climbing -Mountain biking -Mountaineering -Nordic skiing -Rafting -Rock climbing -Sea kayaking -Snowshoeing -Whitewater kayaking Throughout the guide, the expert instructors share insights, best practices, and field-tested lesson plans that help you teach essential skills to new outdoor and adventure enthusiasts. Lesson plans include a topic overview, equipment information, basic skill instruction, Leave No Trace practices, and safety considerations. You'll also find outcomes and assessment protocols for each lesson as well as information on modifying some of the activities to include people with disabilities. The format of the lessons provides you with the flexibility to select and use the plans and assessment strategies appropriate for your group's ages, ability levels, time constraints, and settings. Both a classroom and field-friendly guide, Technical Skills for Adventure Programming: A Curriculum Guide supports common practices and standards of the Wilderness Education Association, Outward Bound, Leave No Trace, the American Mountain Guide Association, the American Canoe Association, and the National Association for Sport and Physical Education. And it will prepare those with experience to confidently teach a dozen popular land-based, water-based, and winter activities.

作者：  

出版社：

简介：　　Video Atlas of Oculofacial Plastic and Reconstructive Surgery, by Drs. Bobby S. Korn and Don O. Kikkawa, is the first reference to help perfect your skills and expand your repertoire by giving you access to actual surgical techniques on high-definition, quality video. With three DVD-ROMs and accompanying color surgical text that highlights key stages of every technique presented in the videos, this package helps you master 42 different procedures including upper and lower blepharoplasty, ptosis repair, filler and botulinum toxin injections, and more. The video clips, professionally edited with narration, explain the techniques step by step and provide you with more than three hours of coverage depicting today's latest surgical approaches. 　　 　　 Master hot multiple procedures such as upper and lower blepharoplasty, ptosis repair, endoscopic brow lifting, botulinum toxin, oculofacial reconstruction, eyelid malposition repairs, endoscopic lacrimal surgery, advanced orbital surgery techniques, and more. Follow the surgeons' every move and hear them narrate the techniques on each video clip, step by step. Use the video's freeze frames with digital overlays to view specific areas of interest. Look for the intraoperative, high-definition, digital images of the surgery in the accompanying book chapter that correspond to the surgery shown in each video for easy reference, along with a convenient listing of key surgical steps, sutures, and required instruments. 　　 　　 Master new techniques with unique high-definition oculofacial videos to offer your patients the best outcomes　　

作者：  

出版社：

简介：Written and edited by the global pioneers who introduced and refined the techniques in current use, Interventional Cardiology: Principles and Practice provides comprehensive guidance to best practices and optimal patient care. Designed to aid both trainees in intervention as well as more seasoned practitioners seeking to improve their performance of specific techniques or expand their repertoire, the book emphasizes material selection and angiographic setup for the full range of procedures. Comprehensive chapters address how to approach complex coronary lesions, such as chronic total occlusions, bifurcations, and unprotected left main lesions.

作者：  

出版社：

简介：This edited collection draws on a range of disciplines in exploring the central place of narrative in social inquiry and understanding the ethical life. It provides scholarly and practical insights into the rewards and potential pitfalls of working in, and with narrative. It offers readers a broad range of carefully considered examples; the use of art in enhancing insight into the plights of rural communities in Australia; the use of illness narratives in medical education; and, applying narratives of torture survivors and torturers in shaping humane political response and policy in the face of terrorism, and the place of the music, as a vehicle of story telling and moral growth. This volume illuminates the explicit links between the importance of narrative, that is, the telling of stories to create shape and meaning in our lives, and ethical engagement so critical to the achievement of a good life.

作者：  

出版社：

简介：This casebook presents up-to-date materials on the complex reality of modern American criminal law. It includes edited cases and statutes, substantial chapter introductions, and highlights on pedagogical approaches (e.g., rules v. standards). Organized with cross-references to highlight connections, clear conceptual structure, and consideration of Model Penal Code throughout. Cases on recent developments include sentencing guidelines, internet crime, white collar crime, drug offenses, possession offenses, hate crimes, victims' rights, state v. federal power, executive v. legislative criminal lawmaking, and the "war on terror." Also includes materials on common crimes such as shoplifting, traffic offenses, and collateral effects of drug convictions.

作者：  

出版社：

简介：This book describes everything about DNA repeat instability and neurological disorders, covering molecularmechanisms of repeat expansion, pathogenic mechanisms, clinical phenotype, parental gender effects, genotype-phenotype correlation, and diagnostic applications of the molecular data. This updated edition provides excellent updates of these repeat expansion mutations, including theaddition of many new chapters, and old chapters rewritten as extensions of the previous edition. This edition also features a CD-ROM containing all of the figures from the book. This book is an invaluable reference source for neuroscientists, geneticists, neurologists, molecular biologists, genetic counsellors and students. * Includes aCD-ROM with all of the figures * Contributions by most of the principal research teams in the area, edited by world-renowned leaders * Lays the background for future investigations on related diseases.