Quantitative trait loci : methods and protocols /

作者：  edited by Nicola J. Camp and Angela Cox.

出版社：

简介：Presenting statistical methods for the genetic analysis of quantitative traits, 12 contributions review recent methodologies in the areas of human traits underlying disease, experimental organisms as models for human disease, and crop and livestock applications in agriculture. Each chapter examines the steps for proceeding with specific analyses, including discussion of appropriate software, interpretation of results and worked examples. Camp (genetic epidemiology, U. of Utah School of Medicine, US) and Cox (Institute for Cancer Studies, U. of Sheffield Medical School, UK) include examinations of association studies, parametric linkage analysis, join linkage and segregation analysis using Markov chain Monte Carlo methods, experimental designs for qualitative trait locus analysis in mice, and approaches to the analysis of complex quantitative phenotypes and marker map construction based on the analysis of rat models of hypertension. Annotation c. Book News, Inc., Portland, OR (booknews.com)