Morphology methods : cell and molecularbiology techniques /

作者：  edited by Ricardo V.Lloyd ; foreword by Ronald A. DeLellis.

出版社：

简介：Summary: Publisher Summary 1 This reference for pathologists, histologists, anatomists, and cell biologists presents molecular and cell biologic techniques used in the in situ analysis of cells and tissues. Lloyd (Mayo Clinic) and other international researchers and clinicians describe techniques such as laser capture microdissection, Fluorescent In Situ Hybridization (FISH), confocal laser scanning microscopy, and tyramide amplification. Applications discussed include the diagnosis of endocrine and lymphoid lesions, the detection of infectious agents and DNA, and clonality analysis. The text is accompanied throughout by illustrations in black and white and color. Annotation c. Book News, Inc., Portland, OR (booknews.com)   Publisher Summary 2 Ricardo Lloyd, md, phd, provides critical and tutorial surveys of the cutting-edge molecular and cell biologic techniques used today in the analysis of cells and tissues in situ. These molecular-based histologic and morphologic techniques are described in step-by-step detail by hands-on experts, often those who have originated or perfected them. Among the techniques presented are laser capture microdissection, in situ hybridization, FISH, confocal laser scanning microscopy, in situ PCR, and tyramide amplification. Applications include the detection of infectious agents and DNA, the diagnosis of undifferentiated tumors and endocrine lesions, the metaphase analysis of whole blood cultures, and clonality analysis. In its integrated, state-of-the-art approach, Morphology Methods: Cell and Molecular Biology Techniques thoroughly details and applies the rich panoply of significant new cell and molecular biologic technologies to all the major problems confronting morphologic studies and diagnostic pathology today.