简介
Summary:
Publisher Summary 1
Boullata (pharmacy, Temple University) brings together contributors reviewing common and some less common drug-nutrient interactions and clinical approaches to their effective management. The book/CD-ROM package explores every major aspect of the problem, including drug and nutrient disposition, enzyme systems, and the influence of food, nutrients, and non-nutrient components on drug effects and disposition. Separate chapters examine the effects of substances including caffeine, alcohol, and garlic, and reviews offer detailed information on the major drugs that affect the cardiovascular and nervous systems, with emphasis on the antiepileptics. The CD-ROM contains an Adobe e-Book version of the book, which can be viewed on a computer or handheld device. The book can be used as a reference by physicians, pharmacists, dieticians, and food scientists. Annotation 漏2004 Book News, Inc., Portland, OR (booknews.com)
Publisher Summary 2
This benchmark survey of drug-nutrient interactions details the mechanisms and clinical approaches to their effective management. Providing more than a simple listing of common interactions, the authors explore, in-depth, every major aspect of the problem, including drug and nutrient disposition, enzyme systems, the effects of nutritional status on drug disposition, and the influence of food, nutrients, non-nutrient components on drug disposition and effects. They also present the latest findings on the influence of medications on nutrient status and on those interactions relevant to life-cycle stages and to specific patient groups. Separate chapters examine the effects of caffeine, charcoal broiling, grapefruit juice, alcohol, garlic, ginko biloba, dietary minerals, folate, vitamins D and K, and calcium. Extensive tables provide clinical recommendations and organize the data clearly to help the reader evaluate nutrition's critical role in optimizing drug efficacy, especially in at-risk populations.
目录
Series Editor's Introduction p. v
Foreword p. ix
Preface p. xi
Contributors p. xv
Value-Added eBook/PDA p. xvii
I Overview of Drug-Nutrient Interactions
1 A Perspective on Drug-Nutrient Interactions Joseph I. Boullata and Jacqueline R. Barber p. 3
2 Drug Disposition and Response Robert B. Raffa p. 27
3 Drug-Metabolizing Enzymes and P-Glycoprotein Thomas K. H. Chang p. 43
4 Nutrient Disposition and Response Francis E. Rosato, Jr. p. 69
II Influence of Nutritional Status on Drug Disposition and Effect
5 The Impact of Protein-Calorie Malnutrition on Drugs Charlene W. Compher p. 83
6 Influence of Obesity on Drug Disposition and Effect Joseph I. Boullata p. 101
III Influence of Food or Nutrients on Drug Disposition and Effect
7 Drug Absorption With Food David Fleisher and Burgunda V. Sweet and Ameeta Parekh p. 129
8 Effects of Specific Foods and Non-Nutritive Dietary Components on Drug Metabolism Karl E. Anderson p. 155
9 Grapefruit Juice-Drug Interaction Issues David G. Bailey p. 175
10 Nutrients That May Optimize Drug Effects Imad F. Btaiche and Michael D. Kraft p. 195
11 Dietary Supplement Interactions With Medication Jeffrey J. Mucksavage and Lingtak-Neander Chan p. 217
12 Dietary Supplement Interaction With Nutrients Mariana Markell p. 235
IV Influence of Pharmaceuticals on Nutritional Status, Nutrient Disposition, and Effect
13 Drug-Induced Changes to Nutritional Status Jane M. Gervasio p. 243
14 Cardiac Drugs and Nutritional Status Honesto M. Poblete, Jr. and Raymond C. Talucci, II p. 257
15 Drug-Nutrient Interactions Involving Folate Leslie Schechter and Patricia Worthington p. 271
16 Effects of Antiepileptics on Nutritional Status Mary J. Berg p. 285
17 Drug-Nutrient Interactions That Impact Mineral Status Sue A. Shapses and Yvette R. Schlussel and Mariana Cifuentes p. 301
V Drug-Nutrient Interactions by Life Stage
18 Drug-Nutrient Interactions in Infancy and Childhood Deborah A. Maka and Lori Enriquez and Maria R. Mascarenhas p. 331
19 Drug-Nutrient Interaction Considerations in Pregnancy and Lactation Kathleen L. Hoover and Marcia Silkroski and Leslie Schechter and Patricia Worthington p. 345
20 Drug-Nutrient Interactions in the Elderly Tanya C. Knight-Klimas and Joseph I. Boullata p. 363
VI Drug-Nutrient Interactions in Specific Conditions
21 Drug-Nutrient Interactions in Patients With Cancer Todd W. Canada p. 413
22 Drug-Nutrient Interactions in Transplantation Matthew J. Weiss and Vincent T. Armenti and Jeanette M. Hasse p. 425
23 Drug-Nutrient Interactions and Immune Function Adrianne Bendich and Ronit Zilberboim p. 441
24 Drug-Nutrient Interactions in Patients With Chronic Infections Steven P. Gelone and Judith A. O'Donnell p. 479
25 Antimicrobial-Nutrient Interactions: An Overview Allison Wood Wallace p. 499
26 Drug-Nutrient Interactions in Patients Receiving Enteral Nutrition Carol J. Rollins p. 515
Index p. 553
Foreword p. ix
Preface p. xi
Contributors p. xv
Value-Added eBook/PDA p. xvii
I Overview of Drug-Nutrient Interactions
1 A Perspective on Drug-Nutrient Interactions Joseph I. Boullata and Jacqueline R. Barber p. 3
2 Drug Disposition and Response Robert B. Raffa p. 27
3 Drug-Metabolizing Enzymes and P-Glycoprotein Thomas K. H. Chang p. 43
4 Nutrient Disposition and Response Francis E. Rosato, Jr. p. 69
II Influence of Nutritional Status on Drug Disposition and Effect
5 The Impact of Protein-Calorie Malnutrition on Drugs Charlene W. Compher p. 83
6 Influence of Obesity on Drug Disposition and Effect Joseph I. Boullata p. 101
III Influence of Food or Nutrients on Drug Disposition and Effect
7 Drug Absorption With Food David Fleisher and Burgunda V. Sweet and Ameeta Parekh p. 129
8 Effects of Specific Foods and Non-Nutritive Dietary Components on Drug Metabolism Karl E. Anderson p. 155
9 Grapefruit Juice-Drug Interaction Issues David G. Bailey p. 175
10 Nutrients That May Optimize Drug Effects Imad F. Btaiche and Michael D. Kraft p. 195
11 Dietary Supplement Interactions With Medication Jeffrey J. Mucksavage and Lingtak-Neander Chan p. 217
12 Dietary Supplement Interaction With Nutrients Mariana Markell p. 235
IV Influence of Pharmaceuticals on Nutritional Status, Nutrient Disposition, and Effect
13 Drug-Induced Changes to Nutritional Status Jane M. Gervasio p. 243
14 Cardiac Drugs and Nutritional Status Honesto M. Poblete, Jr. and Raymond C. Talucci, II p. 257
15 Drug-Nutrient Interactions Involving Folate Leslie Schechter and Patricia Worthington p. 271
16 Effects of Antiepileptics on Nutritional Status Mary J. Berg p. 285
17 Drug-Nutrient Interactions That Impact Mineral Status Sue A. Shapses and Yvette R. Schlussel and Mariana Cifuentes p. 301
V Drug-Nutrient Interactions by Life Stage
18 Drug-Nutrient Interactions in Infancy and Childhood Deborah A. Maka and Lori Enriquez and Maria R. Mascarenhas p. 331
19 Drug-Nutrient Interaction Considerations in Pregnancy and Lactation Kathleen L. Hoover and Marcia Silkroski and Leslie Schechter and Patricia Worthington p. 345
20 Drug-Nutrient Interactions in the Elderly Tanya C. Knight-Klimas and Joseph I. Boullata p. 363
VI Drug-Nutrient Interactions in Specific Conditions
21 Drug-Nutrient Interactions in Patients With Cancer Todd W. Canada p. 413
22 Drug-Nutrient Interactions in Transplantation Matthew J. Weiss and Vincent T. Armenti and Jeanette M. Hasse p. 425
23 Drug-Nutrient Interactions and Immune Function Adrianne Bendich and Ronit Zilberboim p. 441
24 Drug-Nutrient Interactions in Patients With Chronic Infections Steven P. Gelone and Judith A. O'Donnell p. 479
25 Antimicrobial-Nutrient Interactions: An Overview Allison Wood Wallace p. 499
26 Drug-Nutrient Interactions in Patients Receiving Enteral Nutrition Carol J. Rollins p. 515
Index p. 553
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