Front cover 1
Ocular Pathology 4
Copyright page 5
Table of contents 6
Foreword 8
Forewords 10
Preface 12
Dedication 14
Chapter 1: Basic Principles of Pathology 16
INFLAMMATION 16
IMMUNOBIOLOGY 30
CELLULAR AND TISSUE REACTIONS 37
BIBLIOGRAPHY 40
Chapter 2: Congenital Anomalies 44
PHAKOMATOSES (DISSEMINATED HEREDITARY HAMARTOMAS) 44
CHROMOSOMAL ABERRATIONS 51
INFECTIOUS EMBRYOPATHY 58
DRUG EMBRYOPATHY 60
OTHER CONGENITAL ANOMALIES 60
BIBLIOGRAPHY 67
Chapter 3: Nongranulomatous Inflammation: Uveitis, Endophthalmitis, Panophthalmitis, and Sequelae 72
DEFINITION 72
CLASSIFICATION 72
SUPPURATIVE ENDOPHTHALMITIS AND PANOPHTHALMITIS 74
NONSUPPURATIVE, CHRONIC NONGRANULOMATOUS UVEITIS AND ENDOPHTHALMITIS 76
SEQUELAE OF UVEITIS, ENDOPHTHALMITIS, AND PANOPHTHALMITIS 82
END STAGE OF DIFFUSE OCULAR DISEASES 85
BIBLIOGRAPHY 86
Chapter 4: Granulomatous Inflammation 88
INTRODUCTION 88
POSTTRAUMATIC 88
NONTRAUMATIC INFECTIONS 92
NONTRAUMATIC NONINFECTIOUS 108
BIBLIOGRAPHY 113
Chapter 5: Surgical and Nonsurgical Trauma 120
CAUSES OF ENUCLEATION 120
COMPLICATIONS OF INTRAOCULAR SURGERY 120
COMPLICATIONS OF NEURAL RETINAL DETACHMENT AND VITREOUS SURGERY 138
COMPLICATIONS OF CORNEAL SURGERY 144
COMPLICATIONS OF GLAUCOMA SURGERY 148
COMPLICATIONS OF NONSURGICAL TRAUMA 149
BIBLIOGRAPHY 171
Chapter 6: Skin and Lacrimal Drainage System 180
NORMAL ANATOMY 180
TERMINOLOGY 180
CONGENITAL ABNORMALITIES 183
AGING 187
INFLAMMATION 188
LID MANIFESTATIONS OF SYSTEMIC DERMATOSES OR DISEASE 193
CYSTS, PSEUDONEOPLASMS, AND NEOPLASMS 203
NORMAL ANATOMY 224
CONGENITAL ABNORMALITIES 225
INFLAMMATION\u2014DACRYOCYSTITIS 225
TUMORS 226
BIBLIOGRAPHY 228
Chapter 7: Conjunctiva 238
NORMAL ANATOMY 238
CONGENITAL ANOMALIES 240
VASCULAR DISORDERS 240
INFLAMMATION 241
INJURIES 250
CONJUNCTIVAL MANIFESTATIONS OF SYSTEMIC DISEASE 250
DEGENERATIONS 251
CYSTS, PSEUDONEOPLASMS, AND NEOPLASMS 255
BIBLIOGRAPHY 264
Chapter 8: Cornea and Sclera 270
NORMAL ANATOMY 270
CONGENITAL DEFECTS 272
INFLAMMATIONS\u2014NONULCERATIVE 281
INFLAMMATIONS\u2014ULCERATIVE 284
INFLAMMATIONS\u2014CORNEAL SEQUELAE 289
INJURIES 289
DEGENERATIONS 289
DYSTROPHIES 300
PIGMENTATIONS 324
INFECTIONS 328
NEOPLASM 329
CONGENITAL ANOMALIES 329
INFLAMMATIONS 330
TUMORS 332
BIBLIOGRAPHY 334
Chapter 9: Uvea 348
NORMAL ANATOMY 348
CONGENITAL AND DEVELOPMENTAL DEFECTS 348
CONGENITAL AND DEVELOPMENTAL DEFECTS OF THE PIGMENT EPITHELIUM 351
INFLAMMATIONS 356
INJURIES 356
SYSTEMIC DISEASES 357
ATROPHIES AND DEGENERATIONS 359
DYSTROPHIES 361
TUMORS 364
UVEAL EDEMA (UVEAL DETACHMENT; UVEAL HYDROPS) 370
BIBLIOGRAPHY 372
Chapter 10: Lens 376
NORMAL ANATOMY 376
GENERAL INFORMATION 376
CONGENITAL ANOMALIES 376
CAPSULE (EPITHELIAL BASEMENT MEMBRANE) 380
EPITHELIUM 388
ELSCHNIG\u2019S PEARLS 389
CORTEX AND NUCLEUS (LENS CELLS OR \u201cFIBERS\u201d) 390
SECONDARY CATARACTS 395
COMPLICATIONS OF CATARACTS 399
ECTOPIC LENS 400
BIBLIOGRAPHY 404
Chapter 11: Neural (Sensory) Retina 408
NORMAL ANATOMY 408
CONGENITAL ANOMALIES 409
VASCULAR DISEASES 415
INFLAMMATIONS 431
INJURIES 433
DEGENERATIONS 433
HEREDITARY PRIMARY RETINAL DYSTROPHIES 452
HEREDITARY SECONDARY RETINAL DYSTROPHIES 465
SYSTEMIC DISEASES INVOLVING THE RETINA 472
TUMORS 472
NEURAL RETINAL DETACHMENT 477
BIBLIOGRAPHY 485
Chapter 12: Vitreous 496
NORMAL ANATOMY 496
CONGENITAL ANOMALIES 496
INFLAMMATION 498
VITREOUS ADHESIONS 498
VITREOUS OPACITIES 498
VITREOUS HEMORRHAGE 507
BIBLIOGRAPHY 509
Chapter 13: Optic Nerve 512
NORMAL ANATOMY 512
CONGENITAL DEFECTS AND ANATOMIC VARIATIONS 513
OPTIC DISC EDEMA 520
OPTIC NEURITIS 522
OPTIC ATROPHY 528
INJURIES 529
TUMORS 529
BIBLIOGRAPHY 538
Chapter 14: Orbit 544
NORMAL ANATOMY 544
EXOPHTHALMOS 544
DEVELOPMENTAL ABNORMALITIES 546
ORBITAL INFLAMMATION 547
INJURIES 549
VASCULAR DISEASE 551
OCULAR MUSCLE INVOLVEMENT IN SYSTEMIC DISEASE 551
NEOPLASMS AND OTHER TUMORS 555
BIBLIOGRAPHY 600
Chapter 15: Diabetes Mellitus 610
NATURAL HISTORY 610
RETINAL VASCULATURE IN NORMAL SUBJECTS AND DIABETIC PATIENTS 611
CONJUNCTIVA AND CORNEA 611
LENS 614
IRIS 614
CILIARY BODY AND CHOROID 617
NEUROSENSORY RETINA 617
VITREOUS 633
OPTIC NERVE 634
BIBLIOGRAPHY 635
Chapter 16: Glaucoma 640
NORMAL ANATOMY 640
INTRODUCTION 642
NORMAL OUTFLOW 644
IMPAIRED OUTFLOW 644
TISSUE CHANGES CAUSED BY ELEVATED INTRAOCULAR PRESSURE 669
BIBLIOGRAPHY 675
Chapter 17: Ocular Melanocytic Tumors 682
NORMAL ANATOMY 682
MELANOTIC TUMORS OF EYELIDS 682
MELANOTIC TUMORS OF CONJUNCTIVA 691
MELANOTIC TUMORS OF PIGMENT EPITHELIUM OF IRIS, CILIARY BODY, AND RETINA 699
MELANOTIC TUMORS OF THE UVEA 708
MELANOTIC TUMORS OF THE OPTIC DISC AND OPTIC NERVE 736
MELANOTIC TUMORS OF THE ORBIT 737
BIBLIOGRAPHY 738
Chapter 18: Retinoblastoma and Pseudoglioma 748
RETINOBLASTOMA 748
PSEUDOGLIOMA 761
BIBLIOGRAPHY 773
Index 780