Biomolecular action of ionizing radiation /

作者：  edited by Shirley Lehnert.

出版社：

简介：Summary: Publisher Summary 1 Writing for residents in radiation oncology, medical physicists, and others interested in the radiation sciences and cancer treatment, Lehnert (Montreal General Hospital/McGill U., Canada) presents a textbook on molecular radiation biology that is biased towards those aspects that may contribute to improvements in the treatment of cancer with ionizing radiation. Over the course of 17 chapters he covers basic radiation physics and chemistry; basic cell biology and molecular genetics; methods of cell and molecular radiology; ionizing radiation effects to the cytoplasm; damage to DNA by ionizing radiation; repair of radiation damage to DNA; cellular response to DNA damage; chromatin structure and radiation sensitivity; radiation-induced chromosome damage; modulation of radiation responses via signal transduction pathways; radiation-induced apoptosis; early and late responding genes induced by ionizing radiation; cell death, cell survival, and adaptation; bystander effects and genomic instability; tumor radiation biology; and radiation biology of nonmammalian species (three eukaryotes and a bacterium). Annotation 漏2008 Book News, Inc., Portland, OR (booknews.com)