Cell-cell interactions. 2nd ed. /

作者：  Fleming, Tom P.

出版社：

简介：Summary: Publisher Summary 1 Approaches and techniques are described for use in studying cell-cell interactions, focusing on biological processes where cell-cell interactions have been shown to play a critical role. Methodologies are given for working with specialized cell types, specialized domains of membrane contact, different developmental models of mammalian development, and distinct stages of medical importance. Protocols span molecular, cellular, biochemical, and physiological techniques. This second edition reflects recent developments in classical procedures. Fleming teaches in the School of Biological Sciences at the University of Southampton, UK. Annotation c. Book News, Inc., Portland, OR (booknews.com)   Publisher Summary 2 The book comprises ten chapters written by experts in the field on cell-cell interactions and their role in biology and medicine. Cell-cell interactions are the means by which cells are able to communicate, transfer information, develop spatial awareness and coordinate their differentiation. The ten areas have been selected for their breadth and relevance to modern research scientists where cell-cell interactions have been shown to play a critical role in biological processes. Chapters include methodologies for specialised cell types (keratinocytes, leukocytes, neurons, endothelial cells), specialised domains of membrane contact (adhesion molecules, gap junctions, tight junctions), different developmental models (Drosophila, Xenopus, mouse) and, for mammalian development, distinct stages of medical importance (oocyte-granulosa cells; preimplantation embryos; implantation). Throughout, molecular, cellular, biochemical and physiological protocols are provided in comprehensive detail to help the reader develop new skills and understanding.