In situ hybridization in electron microscopy /

Summary: Publisher Summary 1 Provides techniques and protocols for visualizing specific nucleic acid sequences in tissue and single-cell preparations through electron microscopy. Combines theory and practice, starting with basic principles, then breaks down the experimental process into successive steps illustrated by diagrams, protocols, and tables for choosing the right protocol. Information is given in parallel columns to convey practical comments and advice. Coverage encompasses tissue preparation, section preparation, pretreatment, hybridization, controls and problems, and protocol types. Separate appendices provide information on the preparation of equipment and reagents. For experienced and novice researchers. Morel is affiliated with the National Center of Scientific Research, France. Annotation c. Book News, Inc., Portland, OR (booknews.com)