Unraveling lipid metabolism with microarrays /
副标题：无
作 者：edited by Alvin Berger, Matthew A. Roberts.
分类号：
ISBN：9780824758110
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简介
"Spanning technologies in genomics, transcriptomics, and metabolomics, this reference demonstrates the utilization of microarrays and transcriptomic approaches to clarify the biological function of lipids - reviewing current studies and previously unpublished research from leading laboratories around the world."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved
Reviewing current studies and previously unpublished research from leading laboratories around the world, Unraveling Lipid Metabolism with Microarrays demonstrates the use of microarrays and transcriptomic approaches to clarify the biological function of lipids. With contributions from world-class researchers, the book focuses on the use of microarrays to study and understand lipid metabolism.
With coverage that spans the technologies of genomics, transriptomics, and meatabolomics, the text contains reviews of published work, provides a fresh look at new data, and presents previously unpublished work. It explores the role of fatty acids in gene expression and the various effects lipids have on the cell cycle, cholesterol metabolism, and insulin secretion. Taking a proteomic approach to looking at lipids, the book covers a wide variety of subjects, all linked to the study of lipid metabolism.
目录
Front Matter
Chapter 1. Statistical Design and Data Analysis for Microarray Experiments
Darlene R. Goldstein, Mauro Delorenzi
Chapter 2. Dietary Effects of Arachidonate-Rich Fungal Oil and Fish Oil on Murine Hepatic Gene Expression
Matthew A. Roberts, Alvin Berger
Chapter 3. Dietary Effects of Arachidonate-Rich Fungal Oil and Fish Oil on Murine Hippocampal Gene Expression
Matthew A. Roberts, Alvin Berger
Chapter 4. Exploring the Effects of Polyunsaturated Fatty Acids on Gene Expression in Human Hepatocyte (HepG2 Cells) Using DNA Chip
Yoko Fujiwara, Akiyo Masumoto
Chapter 5. Neurological Effects of Dietary n-3 Fatty Acids in Rat Brain
Gwendolyn Barcel鈭氣墺-Coblijn, Tibor Farkas, L鈭毬皊zl鈭氣墺 G. Pusk鈭毬皊, Kl鈭毬皉a Kitajka
Chapter 6. Anterior and Posterior Cerebral Gene Expression in a Rat Model of Reduced Brain Docosahexaenoic Acid During Development
Susan E. Carlson, Judy B. Gaines, Nancy E. J. Berman
Chapter 7. A Genomic Approach to Studying Leptin Signaling in a Hypothalamic Cell Line
Wiweka Kaszubska, Paul Hessler, Paul E. Kroeger
Chapter 8. Characterizing Cholesterol Metabolism in Atherosclerosis Susceptible and Resistant Mouse Models Using DNA Microarrays
Karen Reue, Laurent Vergnes, Jack Phan
Chapter 9. Microarray Analysis of Lipid Metabolism in Drug Abuse, Neurological and Psychiatric Disorders
E. Lehrmann, J. Chen, C. -T. Lee, W. J. Freed, K. G. Becker
Chapter 10. Microarray Analyses of SREBP-1 Target Genes
Naoya Yahagi, Hitoshi Shimano
Chapter 11. Understanding the Coordinated Effects of PPARs on Lipid Metabolism Using Microarrays
Walter Wahli, Pascal Escher, Sander Kersten, Sherrie Tafuri
Chapter 14. Omega-3 Polyunsaturated Fatty Acid Against Colon Cancer
Narayanan K. Narayanan, Bhagavathi A. Narayanan, Bandaru S. Reddy
Chapter 15. Ellagic Acid Modulates Lipid Metabolism in Prostate Cancer
Narayanan K. Narayanan, Bhagavathi A. Narayanan, Daniel W. Nixon, Otto Geoffroy
Chapter 16. Changes of Gene Expression in INS-1 cells
Jianzhong Xiao, Abudula Reziwanggu, Torben 鈭毭瞨ntoft, Kjeld Hermansen, Mogens Kruh鈭氣垙ffer, Per Bendix Jeppesen
Chapter 17. Use of Microarrays to Investigate the Transcriptional Effects of Protein Tyrosine Phosphatase IB (PTP1B)
Jeffrey F. Waring, Cristina M. Rondinone
Chapter 18. Metabonomics as a Tool for Understanding Lipid Metabolism
David J. Grainger, Jeremy K. Nicholson, Elaine Holmes, David E. Mosedale
Chapter 19. Zebrafish Model of Lipid Metabolism for Drug Discovery
Steven A. Farber, Amy L. Rubinstein, Shiu-Ying Ho
Chapter 1. Statistical Design and Data Analysis for Microarray Experiments
Darlene R. Goldstein, Mauro Delorenzi
Chapter 2. Dietary Effects of Arachidonate-Rich Fungal Oil and Fish Oil on Murine Hepatic Gene Expression
Matthew A. Roberts, Alvin Berger
Chapter 3. Dietary Effects of Arachidonate-Rich Fungal Oil and Fish Oil on Murine Hippocampal Gene Expression
Matthew A. Roberts, Alvin Berger
Chapter 4. Exploring the Effects of Polyunsaturated Fatty Acids on Gene Expression in Human Hepatocyte (HepG2 Cells) Using DNA Chip
Yoko Fujiwara, Akiyo Masumoto
Chapter 5. Neurological Effects of Dietary n-3 Fatty Acids in Rat Brain
Gwendolyn Barcel鈭氣墺-Coblijn, Tibor Farkas, L鈭毬皊zl鈭氣墺 G. Pusk鈭毬皊, Kl鈭毬皉a Kitajka
Chapter 6. Anterior and Posterior Cerebral Gene Expression in a Rat Model of Reduced Brain Docosahexaenoic Acid During Development
Susan E. Carlson, Judy B. Gaines, Nancy E. J. Berman
Chapter 7. A Genomic Approach to Studying Leptin Signaling in a Hypothalamic Cell Line
Wiweka Kaszubska, Paul Hessler, Paul E. Kroeger
Chapter 8. Characterizing Cholesterol Metabolism in Atherosclerosis Susceptible and Resistant Mouse Models Using DNA Microarrays
Karen Reue, Laurent Vergnes, Jack Phan
Chapter 9. Microarray Analysis of Lipid Metabolism in Drug Abuse, Neurological and Psychiatric Disorders
E. Lehrmann, J. Chen, C. -T. Lee, W. J. Freed, K. G. Becker
Chapter 10. Microarray Analyses of SREBP-1 Target Genes
Naoya Yahagi, Hitoshi Shimano
Chapter 11. Understanding the Coordinated Effects of PPARs on Lipid Metabolism Using Microarrays
Walter Wahli, Pascal Escher, Sander Kersten, Sherrie Tafuri
Chapter 14. Omega-3 Polyunsaturated Fatty Acid Against Colon Cancer
Narayanan K. Narayanan, Bhagavathi A. Narayanan, Bandaru S. Reddy
Chapter 15. Ellagic Acid Modulates Lipid Metabolism in Prostate Cancer
Narayanan K. Narayanan, Bhagavathi A. Narayanan, Daniel W. Nixon, Otto Geoffroy
Chapter 16. Changes of Gene Expression in INS-1 cells
Jianzhong Xiao, Abudula Reziwanggu, Torben 鈭毭瞨ntoft, Kjeld Hermansen, Mogens Kruh鈭氣垙ffer, Per Bendix Jeppesen
Chapter 17. Use of Microarrays to Investigate the Transcriptional Effects of Protein Tyrosine Phosphatase IB (PTP1B)
Jeffrey F. Waring, Cristina M. Rondinone
Chapter 18. Metabonomics as a Tool for Understanding Lipid Metabolism
David J. Grainger, Jeremy K. Nicholson, Elaine Holmes, David E. Mosedale
Chapter 19. Zebrafish Model of Lipid Metabolism for Drug Discovery
Steven A. Farber, Amy L. Rubinstein, Shiu-Ying Ho
Unraveling lipid metabolism with microarrays /
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