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ISBN:9781555812096

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Summary: Publisher Summary 1 This volume represents an extension of Mobile DNA published by ASM Press in 1989, and reflects the rapidity with which advances in the field have occurred. It documents the mobility of DNAs in procaryotic and eucaryotic genomes (the ability of various segments to move to new sites, to invert, and to undergo deletion or amplification, generally without the extensive DNA sequence homology needed for classical recombination), as well as the variety of mechanisms by which these rearrangements occur, how they are regulated, their biological consequences, and ways in which transposable elements can be exploited as potent research tools. The 49 contributions are intended to serve both experienced scientists and students, and detail phenomena from a wide range of organisms. Edited by Craig (John Hopkins U. School of Medicine), Robert Craigie and Martin Gellert (both of the National Institute of Diabetes and Digestive and Kidney Diseases), and Alan M. Lambowitz (biological sciences, U. of Texas). Annotation c. Book News, Inc., Portland, OR (booknews.com)  

目录

Contributors p. ix
Preface p. xv
Preface to Mobile DNA (1989) p. xvii
I. Introduction to Mobile DNAs: What They Are, Their Cellular Roles, How They Move, and How To Exploit Them
1. Mobile DNA: an Introduction Nancy L. Craig p. 3
2. Chemical Mechanisms for Mobilizing DNA Kiyoshi Mizuuchi and Tania A. Baker p. 12
3. Putting Mobile DNA to Work: the Toolbox Jef D. Boeke p. 24
4. Chromosome Manipulation by Cre-lox Recombination Brian Sauer p. 38
5. Transposable Elements as Sources of Genomic Variation Margaret G. Kidwell and Damon R. Lisch p. 59
II. Conservative Site-Specific Recombination: Rearrangements That Involve Covalent Protein-DNA Intermediates
6. A Structural View of Tyrosine Recombinase Site-Specific Recombination Gregory D. Van Duyne p. 93
7. [lambda] Integrase and the [lambda] Int Family Marco A. Azaro and Arthur Landy p. 118
8. Xer Site-Specific Recombination: Promoting Chromosome Segregation Francois-Xavier Barre and David J. Sherratt p. 149
9. Gene Acquisition in Bacteria by Integron-Mediated Site-Specific Recombination Gavin D. Recchia and David J. Sherratt p. 162
10. Conjugative Transposons and Related Mobile Elements Gordon Churchward p. 177
11. Site-Specific Recombination by the Flp Protein of Saccharomyces cerevisiae Makkuni Jayaram and Ian Grainge and Gena Tribble p. 192
12. Theme and Variation in Tyrosine Recombinases: Structure of a Flp-DNA Complex Phoebe A. Rice p. 219
13. Bacterial Site-Specific DNA Inversion Systems Reid C. Johnson p. 230
14. The Movement of Tn3-Like Elements: Transposition and Cointegrate Resolution Nigel D. F. Grindley p. 272
III. Recombination via Direct Transesterifications: Transposition Reactions That Involve Only DNA Intermediates
15. Insertion Sequences Revisited Michael Chandler and Jacques Mahillon p. 305
16. Transposition of IS911 P. Rousseau and C. Normand and C. Loot and C. Turlan and R. Alazard and G. Duval-Valentin and M. Chandler p. 367
17. Transposition of Phage Mu DNA George Chaconas and Rasika M. Harshey p. 384
18. Tn5 Transposition William S. Reznikoff p. 403
19. Tn7 Nancy L. Craig p. 423
20. Transposon Tn10 David B. Haniford p. 457
21. P Transposable Elements in Drosophila melanogaster Donald C. Rio p. 484
22. The Tc1/mariner Family of Transposable Elements Ronald H. A. Plasterk and Henri G. A. M. van Luenen p. 519
23. MuDR/Mu Transposable Elements of Maize Virginia Walbot and George N. Rudenko p. 533
24. The hAT and CACTA Superfamilies of Plant Transposons Reinhard Kunze and Clifford F. Weil p. 565
IV. Recombination via Direct Transesterifications: Transposition Reactions That Involve RNA and DNA Intermediates
25. Retroviral DNA Integration Robert Craigie p. 613
26. Ty1 and Ty5 of Saccharomyces cerevisiae Daniel F. Voytas and Jef D. Boeke p. 631
27. Ty3, a Position-Specific, Gypsy-Like Element in Saccharomyces cerevisiae Suzanne B. Sandmeyer and Michael Aye and Thomas Menees p. 663
28. Newly Identified Retrotransposons of the Ty3/gypsy Class in Fungi, Plants, and Vertebrates Henry L. Levin p. 684
V. Gene Assembly by Recombination
29. V(D)J Recombination Martin Gellert p. 705
30. Genome-Wide Rearrangements of DNA in Ciliates Meng-Chao Yao and Sandra Duharcourt and Douglas L. Chalker p. 730
VI. Non-Long Terminal Repeat Elements: Target-Primed Reverse Transcription
31. Mobile Introns: Pathways and Proteins Marlene Belfort and Victoria Derbyshire and Monica M. Parker and Benoit Cousineau and Alan M. Lambowitz p. 761
32. Retrons Kunitoshi Yamanaka and Tadashi Shimamoto and Sumiko Inouye and Masayori Inouye p. 784
33. I Elements in Drosophila melanogaster Alain Bucheton and Isabelle Busseau and Danielle Teninges p. 796
34. R2 and Related Site-Specific Non-Long Terminal Repeat Retrotransposons Thomas H. Eickbush p. 813
35. Mammalian LINE-1 Retrotransposons and Related Elements John V. Moran and Nicolas Gilbert p. 836
36. Telomeres and Transposable Elements Mary-Lou Pardue and P. G. DeBaryshe p. 870
VII. Other Mobile DNAs
37. IS91 Rolling-Circle Transposition M. Pilar Garcillan-Barcia and Irantzu Bernales and M. Victoria Mendiola and Fernando de la Cruz p. 891
38. Adeno-Associated Virus Richard H. Smith, Jr. and Robert M. Kotin p. 905
VIII. Transfer of Information via Gene Conversions
39. Switching of Saccharomyces cerevisiae Mating-Type Genes James E. Haber p. 927
40. Antigenic Variation in Eukaryotic Parasites Piet Borst p. 953
41. Antigenic Variation by Relapsing Fever Borrelia Species and Other Bacterial Pathogens Alan Barbour p. 972
IX. Genomes and Mobile DNAs
42. Control of Mobile DNA Nina Fedoroff p. 997
43. Interactions between Transposable Elements and the Host Genome Mariano Labrador and Victor G. Corces p. 1008
44. Eubacterial Genomes Allan Campbell p. 1024
45. Mobile Genetic Elements and Bacterial Pathogenesis Brigid M. Davis and Matthew K. Waldor p. 1040
46. Archaeal Mobile DNA Peter Redder and David Faguy and Kim Brugger and Qunxin She and Roger A. Garrett p. 1060
47. Mobile Elements in Animal and Plant Genomes Prescott L. Deininger and Astrid M. Roy-Engel p. 1074
48. Evolution of DNA Transposons in Eukaryotes Hugh M. Robertson p. 1093
49. Origins and Evolution of Retrotransposons Thomas H. Eickbush and Harmit S. Malik p. 1111
X. Newly Discovered Transposon Families
50. Miniature Inverted-Repeat Transposable Elements and Their Relationship to Established DNA Transposons Cedric Feschotte and Xiaoyu Zhang and Susan R. Wessler p. 1147
Index p. 1159

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