Handbook of glycosyltransferases and related genes /
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作 者：edited by Naoyuki Taniguchi, Koichi Honke, Minoru Fukuda ; co-editors, Henrik Clausen ... [et. al.]
分类号：
ISBN：9784431703112
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简介
This handbook provides comprehensive information on all known glycosyltransferases and their related genes. Nearly 100 chapters, contributed by experts in the field, compile the latest information in a concise format for easy reference. Readers have access to the databases for each glycogene with the accession numbers in each chapter, and maps of biosynthetic pathways of glycoconjugates are also given. The book deals comprehensively with enzymes involved in the biosynthesis of carbohydrate chains of glycoconjugates whose genes have been cloned. Application of gene technology to these enzymes has brought significant progress in glycobiology and glycotechnology in the past decade, making knowledge of the glycogenes that encode glycosyltransferases and related enzymes a shortcut to understanding glycobiology. This handbook is essential for research in functional glycomics, integrating glycobiology and glycotechnology, as it comes of age in the post-genomic era.
目录
Glucosyltransferase
GlcCer Synthase (UDP-Glucose:Ceramide Glucosyltransferase, UGCG
Galactosyltransferases
b4-Galactosyltransferase-I
b4-Galactosyltransferase-II, -III, -IV, -V, -VI, and -VII
b3-Galactosyltransferase-I , -II, and -III
b3-Galactosyltransferase-IV (GM1 Synthase
b3-Galactosyltransferase-V
a3-Galactosyltransferase
GalCer Synthase (Ceramide Galactosyltransferase, CGT
N-Acetylglucosaminyltransferases
N-Acetylglucosaminyltransferase-I
N-Acetylglucosaminyltransferase-II
N-Acetylglucosaminyltransferase-III
N-Acetylglucosaminyltransferase-IV
N-Acetylglucosaminyltransferase-V
N-Acetylglucosaminyltransferase-VI
b3-N-Acetylglucosaminyltransferase (Fringe
b3-N-Acetylglucosaminyltransferase (iGnT
b6-N-Acetylglucosaminyltransferase (IGnT
Core 2 b6-N-Acetylglucosaminyltransferase-1 and -3
Core 2 b6-N-Acetylglucosaminyltransferase-2
a4-N-Acetylglucosaminyltransferase
O-GlcNAc Transferase
N-Acetylgalactosaminyltransferases
Polypeptide N-Acetylgalactosaminyltransferases
b4-N-Acetylgalactosaminyltransferase
Histoblood Groups A and B Transferases, Their Gene Structures, and Common O Group Gene Structures
Histoblood Group A Variants, O Variants, and Their Alleles
Forssman Glycolipid Synthase
Fucosyltransferases
a2-Fucosyltransferases (FUT1, FUT2, and Sec1
a3/4-Fucosyltransferase (FUT3, Lewis Enzyme
a3-Fucosyltransferase-IV (FUT4
a3-Fucosyltransferase-V (FUT5
a3-Fucosyltransferase-VI (FUT6
a3-Fucosyltransferase-VII (FUT7
a3-Fucosyltransferase-IX (FUT9
a6-Fucosyltransferase (FUT8
Sialyltransferases
ST3Gal-I
ST3Gal-II (SAT-IV
ST3Gal-III
ST3Gal-IV
ST3Gal-V (GM3
ST6Gal-I
ST6GalNAc-I
ST6GalNAc-II
ST6GalNAc-III (STY
ST6GalNAc-IV
ST8Sia-I (GD3
ST8Sia-II (STX
ST8Sia-III
ST8Sia-IV (PST-1
ST8Sia-V (SAT-V/SAT-III
CMP-NeuAc Hydroxylase
Glucuronyltransferases
HNK-1
GAG Glucuronyltransferase-I
UDP-Glucose Dehydrogenase
GAG Synthesis
a4-N-Acetylhexosaminyltransferase (EXTL2
Hyaluronan Synthase-1, -2, and -3
Heparan Sulfate GlcA/GlcNAc Transferase
D-Glucuronyl C5-Epimerase in Heparin/Heparan Sulfate Biosynthesis
Sulfotransferases
Chondroitin 6-Sulfotransferase
Keratan Sulfate Gal-6-Sulfotransferase
Corneal N-Acetylglucosamine 6-O-Sulfotransferase
N-Acetylglucosamine-6-O-Sulfotransferase
Intestinal N-Acetylglucosamine 6-O-Sulfotransferase
High Endothelial Cell N-Acetylglucosamine6-O-Sulfotransferase
Chondroitin 4-Sulfotransferase
HNK-1
Galactosaminoglycan Uronyl 2-Sulfotransferase
Heparan Sulfate 2-Sulfotransferase
Heparan Sulfate 6-Sulfotransferase
Heparan Sulfate D-Glucosaminyl 3-O-Sulfotransferase-1, -2, and -3
Heparan Sulfate N-Sulfotransferase-1
Heparan Sulfate N-Sulfotransferase-2
Heparan Sulfate N-Sulfotransferase-3 and -4
bGal 3-O-Sulfotransferase-1, -2, -3, and -4
Nucleotide Sugar Transporters
UDP-Gal Transporter-1
UDP-GlcNAc Transporter
CMP-Sialic Acid Transporter
Dolichol Pathway/GPI-Anchor
GPI-GlcNAc Transferase: Complex of PIG-A, PIG-C, PIG-H, hGPI1, and PIG-P
Dolichol Phospho-Mannose Synthase (DPM1 and DPM2
PIG-B, GPI-Man Transferase III, Man-(Ethanolaminephosphate)Man-GlcN-(Acyl)PI Mannosyltransferase
Dolichol Phosphate GlcNAc-1-P Transferase
ALG3
ALG6
N-Glycan Processing Enzymes
Oligosaccharyltransferase Complex, Ribophorin-I, Ribophorin-II, OST48, and DAD1
Phosphomannomutase
Phosphomannose Isomerase
a-Mannosidase-II
a-Mannosidase-IIx
Lysosomal Enzyme GlcNAc-1-phoshotransferase
GlcNAc-1-Phosphodiester a-N-Acetylglucosaminidase
Appendix
Biosynthetic Pathways of N-Glycans
Biosynthetic Pathways of O-Glycans
Biosynthetic Pathways of Glycosphingolipids
Biosynthetic Pathways of Proteoglycans
Biosynthetic Pathways of GPI-Anchor
GlcCer Synthase (UDP-Glucose:Ceramide Glucosyltransferase, UGCG
Galactosyltransferases
b4-Galactosyltransferase-I
b4-Galactosyltransferase-II, -III, -IV, -V, -VI, and -VII
b3-Galactosyltransferase-I , -II, and -III
b3-Galactosyltransferase-IV (GM1 Synthase
b3-Galactosyltransferase-V
a3-Galactosyltransferase
GalCer Synthase (Ceramide Galactosyltransferase, CGT
N-Acetylglucosaminyltransferases
N-Acetylglucosaminyltransferase-I
N-Acetylglucosaminyltransferase-II
N-Acetylglucosaminyltransferase-III
N-Acetylglucosaminyltransferase-IV
N-Acetylglucosaminyltransferase-V
N-Acetylglucosaminyltransferase-VI
b3-N-Acetylglucosaminyltransferase (Fringe
b3-N-Acetylglucosaminyltransferase (iGnT
b6-N-Acetylglucosaminyltransferase (IGnT
Core 2 b6-N-Acetylglucosaminyltransferase-1 and -3
Core 2 b6-N-Acetylglucosaminyltransferase-2
a4-N-Acetylglucosaminyltransferase
O-GlcNAc Transferase
N-Acetylgalactosaminyltransferases
Polypeptide N-Acetylgalactosaminyltransferases
b4-N-Acetylgalactosaminyltransferase
Histoblood Groups A and B Transferases, Their Gene Structures, and Common O Group Gene Structures
Histoblood Group A Variants, O Variants, and Their Alleles
Forssman Glycolipid Synthase
Fucosyltransferases
a2-Fucosyltransferases (FUT1, FUT2, and Sec1
a3/4-Fucosyltransferase (FUT3, Lewis Enzyme
a3-Fucosyltransferase-IV (FUT4
a3-Fucosyltransferase-V (FUT5
a3-Fucosyltransferase-VI (FUT6
a3-Fucosyltransferase-VII (FUT7
a3-Fucosyltransferase-IX (FUT9
a6-Fucosyltransferase (FUT8
Sialyltransferases
ST3Gal-I
ST3Gal-II (SAT-IV
ST3Gal-III
ST3Gal-IV
ST3Gal-V (GM3
ST6Gal-I
ST6GalNAc-I
ST6GalNAc-II
ST6GalNAc-III (STY
ST6GalNAc-IV
ST8Sia-I (GD3
ST8Sia-II (STX
ST8Sia-III
ST8Sia-IV (PST-1
ST8Sia-V (SAT-V/SAT-III
CMP-NeuAc Hydroxylase
Glucuronyltransferases
HNK-1
GAG Glucuronyltransferase-I
UDP-Glucose Dehydrogenase
GAG Synthesis
a4-N-Acetylhexosaminyltransferase (EXTL2
Hyaluronan Synthase-1, -2, and -3
Heparan Sulfate GlcA/GlcNAc Transferase
D-Glucuronyl C5-Epimerase in Heparin/Heparan Sulfate Biosynthesis
Sulfotransferases
Chondroitin 6-Sulfotransferase
Keratan Sulfate Gal-6-Sulfotransferase
Corneal N-Acetylglucosamine 6-O-Sulfotransferase
N-Acetylglucosamine-6-O-Sulfotransferase
Intestinal N-Acetylglucosamine 6-O-Sulfotransferase
High Endothelial Cell N-Acetylglucosamine6-O-Sulfotransferase
Chondroitin 4-Sulfotransferase
HNK-1
Galactosaminoglycan Uronyl 2-Sulfotransferase
Heparan Sulfate 2-Sulfotransferase
Heparan Sulfate 6-Sulfotransferase
Heparan Sulfate D-Glucosaminyl 3-O-Sulfotransferase-1, -2, and -3
Heparan Sulfate N-Sulfotransferase-1
Heparan Sulfate N-Sulfotransferase-2
Heparan Sulfate N-Sulfotransferase-3 and -4
bGal 3-O-Sulfotransferase-1, -2, -3, and -4
Nucleotide Sugar Transporters
UDP-Gal Transporter-1
UDP-GlcNAc Transporter
CMP-Sialic Acid Transporter
Dolichol Pathway/GPI-Anchor
GPI-GlcNAc Transferase: Complex of PIG-A, PIG-C, PIG-H, hGPI1, and PIG-P
Dolichol Phospho-Mannose Synthase (DPM1 and DPM2
PIG-B, GPI-Man Transferase III, Man-(Ethanolaminephosphate)Man-GlcN-(Acyl)PI Mannosyltransferase
Dolichol Phosphate GlcNAc-1-P Transferase
ALG3
ALG6
N-Glycan Processing Enzymes
Oligosaccharyltransferase Complex, Ribophorin-I, Ribophorin-II, OST48, and DAD1
Phosphomannomutase
Phosphomannose Isomerase
a-Mannosidase-II
a-Mannosidase-IIx
Lysosomal Enzyme GlcNAc-1-phoshotransferase
GlcNAc-1-Phosphodiester a-N-Acetylglucosaminidase
Appendix
Biosynthetic Pathways of N-Glycans
Biosynthetic Pathways of O-Glycans
Biosynthetic Pathways of Glycosphingolipids
Biosynthetic Pathways of Proteoglycans
Biosynthetic Pathways of GPI-Anchor
Handbook of glycosyltransferases and related genes /
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