Principles of Medicinal Chemistry 3th. ed.

1. Introduction and History William O. Foye p. 1
2. Medicinals of Plant Origin: Historical Aspects William O. Foye p. 7
3. Biopharmaceutical Properties of Drug Substances Sunil S. Jambhekar p. 12
4. Structural Features and Pharmacologic Activity Ian W. Mathison and William E. Solomons and Richard R. Tidwell p. 25
5. Theoretic Aspects of Drug Design Michael S. Tute and Lemont B. Kier p. 50
6. Molecular Modeling James G. Henkel and Eric M. Billings p. 58
7. Receptors and Drug Action Timothy J. Maher p. 75
8. Drug Metabolism David A. Williams p. 83
9. Volatile Anesthetics Ronald L. Jacoby and Karl A. Nieforth p. 141
10. Central Nervous System Depressants: Sedative-Hypnotics Julius A. Vida p. 154
11. Anticonvulsants Julius A. Vida p. 182
12. Neuroleptics and Anxiolytic Agents John L. Neumeyer and Raymond G. Booth p. 199
13. Drugs Used to Treat Neuromuscular Disorders: Antiparkinsonism Agents and Skeletal Muscle Relaxants John L. Neumeyer and Raymond G. Booth p. 232
14. Analgesics David S. Fries p. 247
15. Central Nervous System Stimulants Karl A. Nieforth and Gerald Gianutsos p. 270
16. Local Anesthetics Matthias C. Lu p. 305
17. Cholinergic Agonists, Acetylcholinesterase Inhibitors, and Cholinergic Antagonists Danny L. Lattin p. 321
18. Adrenergic Drugs Robert K. Griffith and Elizabeth A. Johnson p. 345
19. Cardic Agents: Cardiac Glycosides, Antianginals, and Antiarrhythmic Drugs Ahmed S. Mehanna p. 366
20. Anticoagulants, Coagulants, and Plasma Extenders Richard H. Hammer p. 388
21. Diuretics Gary O. Rankin p. 405
22. Antiallergic and Antiulcer Drugs Maria Di Bella and Daniela Braghiroli and Donald T. Witiak p. 416
23. Cholesterol, Adrenocorticoids, and Sex Hormones Robert W. Brueggemeier and Duane D. Miller and Donald T. Witiak p. 444
24. Antilipidemic Drugs Dennis R. Feller and Larry M. Hagerman and Howard A. I. Newman and Donald T. Witiak p. 499
25. Nonsteroidal Anti-inflammatory Drugs Ronald F. Borne p. 535
26. Drugs Affecting Sugar Metabolism Edmund J. Hengesh p. 581
27. Amino Acids, Peptides, and Proteins Roy L. Kisliuk p. 601
28. Pharmaceutical Biotechnology Robert D. Sindelar p. 622
29. Vitamins and Coenzymes Raymond W. Doskotch and Robert W. Curley, Jr. p. 652
30. Thyroid Function and Thyroid Drugs Alireza Banijamali p. 688
31. Metabolite Antagonism Nitya Anand p. 705
32. Parasite Chemotherapy William O. Foye p. 730
33. Antimycobacterial Agents Thomas L. Lemke p. 747
34. Antibiotics and Antimicrobial Agents Lester A. Mitscher p. 759
35. Antifungal Agents Eugene D. Weinberg p. 803
36. Antiseptics and Disinfectants Thomas L. Lemke p. 812
37. Cancer Chemotherapy William O. Foye and Sisir K. Sengupta p. 822
38. Antiviral Agents Manohar L. Sethi p. 846
39. Approaches to Anti-AIDS Agents Prem Mohan p. 862
40. Hormone Antagonists V. Craig Jordan p. 877
41. Photochemotherapy Francesco Dall'Acqua and Giulio Jori p. 893
42. Pesticides John L. Neumeyer and Raymond G. Booth p. 908
43. Agents for Organ Imaging Raymond E. Counsell and Jamey P. Weichert p. 927
Appendix p. 948
pK[subscript a] Values for Some Drugs and Miscellaneous Organic Acids and Bases
pH Values for Tissue Fluids David A. Williams
Index p. 963