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Summary:
Publisher Summary 1
Based on the highly successful reference work Viral Pathogenesispublished in 1997, this concise, economical version can be used both as an introductory text or for self-education by medical students and biologists alike. This latest edition provides a completely revised overview of the subject with new chapters on innate immunity, emerging viral diseases, and antiviral therapy in a format that is easy to understand without continually referring to additional information. Used by the author in his graduate classes at the University of Pennsylvania, it sets forth the essential principles and discusses the details of how the immune system responds to viral invasion including the treatment and prevention of infection. Illustrated by pertinent examples it is one of the only books devoted exclusively to this topic.
* Offers almost a 20% expansion over the first edition
* Focuses specifically on viral pathogenesis unlike other texts where only a few chapters are devoted to the topic
* Neal Nathanson is one of theprimary authorities in the field and has authored chapters on viral pathogenesis in two of the most well known virology and microbiology titles Field's Virologyand Topley and Wilson's Microbiology
* Now in four color throughout!
目录
List of Co-authors p. vii
Preface p. ix
Introduction p. xi
Part 1 Essentials of Viral Pathogenesis p. 1
1 Historical Roots Neal Nathanson and Frederick A. Murphy p. 3
2 The Sequential Steps in Viral Infection Neal Nathanson and Frederick A. Murphy p. 14
3 Cellular Receptors and Viral Tropism Neal Nathanson and Kathryn V. Holmes p. 27
4 Virus-Cell Interactions Neal Nathanson and Diane E. Griffin p. 41
Part II Host Responses to Viral Infection p. 57
5 Innate Immunity Neal Nathanson and Christine A. Biron p. 59
6 Immune Responses to Viral Infection Neal Nathanson and Rafi Ahmed p. 72
7 Virus-Induced Immunopathology Neal Nathanson and Rafi Ahmed p. 88
8 Virus-Induced Immunosuppression Neal Nathanson and Diane E. Griffin p. 99
Part III Virus-Host Interactions p. 111
9 Viral Virulence Neal Nathanson and Francisco Gonzalez-Scarano p. 113
10 Viral Persistence Neal Nathanson and Francisco Gonzalez-Scarano p. 130
11 Viral Oncogenesis: Retroviruses Neal Nathanson and Harriet L. Robinson p. 146
12 Viral Oncogenesis: DNA Viruses Neal Nathanson and Erle S. Robertson p. 158
13 Host Susceptibility to Viral Diseases Neal Nathanson and Margo A. Brinton p. 174
14 HIV, SIV and the Pathogenesis of AIDS Neal Nathanson and Julie Overbaugh p. 185
Part IV Ecology and Control of Viral Infections p. 201
15 Emergirig Viral Diseases Neal Nathanson and Frederick A. Murphy p. 203
16 Antiviral Therapy Neal Nathanson and Douglas D. Richman p. 221
17 Viral Vaccines Neal Nathanson and Harriet L. Robinson p. 234
Glossary and Abbreviations p. 253
Index p. 259
Preface p. ix
Introduction p. xi
Part 1 Essentials of Viral Pathogenesis p. 1
1 Historical Roots Neal Nathanson and Frederick A. Murphy p. 3
2 The Sequential Steps in Viral Infection Neal Nathanson and Frederick A. Murphy p. 14
3 Cellular Receptors and Viral Tropism Neal Nathanson and Kathryn V. Holmes p. 27
4 Virus-Cell Interactions Neal Nathanson and Diane E. Griffin p. 41
Part II Host Responses to Viral Infection p. 57
5 Innate Immunity Neal Nathanson and Christine A. Biron p. 59
6 Immune Responses to Viral Infection Neal Nathanson and Rafi Ahmed p. 72
7 Virus-Induced Immunopathology Neal Nathanson and Rafi Ahmed p. 88
8 Virus-Induced Immunosuppression Neal Nathanson and Diane E. Griffin p. 99
Part III Virus-Host Interactions p. 111
9 Viral Virulence Neal Nathanson and Francisco Gonzalez-Scarano p. 113
10 Viral Persistence Neal Nathanson and Francisco Gonzalez-Scarano p. 130
11 Viral Oncogenesis: Retroviruses Neal Nathanson and Harriet L. Robinson p. 146
12 Viral Oncogenesis: DNA Viruses Neal Nathanson and Erle S. Robertson p. 158
13 Host Susceptibility to Viral Diseases Neal Nathanson and Margo A. Brinton p. 174
14 HIV, SIV and the Pathogenesis of AIDS Neal Nathanson and Julie Overbaugh p. 185
Part IV Ecology and Control of Viral Infections p. 201
15 Emergirig Viral Diseases Neal Nathanson and Frederick A. Murphy p. 203
16 Antiviral Therapy Neal Nathanson and Douglas D. Richman p. 221
17 Viral Vaccines Neal Nathanson and Harriet L. Robinson p. 234
Glossary and Abbreviations p. 253
Index p. 259
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