Advances in genetics /
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作 者：edited by Jeffrey C. Hall, Jay C. Dunlap, Theodore Firedmann and Francesco Giannelli.
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ISBN：9780120176472
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简介
Summary:
Publisher Summary 1
Advances in Geneticsincreases its focus on modern human genetics and its relation to medicine with the merger of this long-standing serial with Molecular Genetic Medicine. This merger affirms the Academic Press commitment to publish important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.
Genetics, the science of heredity, lies at the heart of biology, and many diseases are impacted by an individuals genetic make-up. The field of genetics is rapidly evolving and new medical break-throughs are occurring as a result of advances in knowledge of genetics. Advances in Genetics continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. This volume of Advances in Geneticscontains the following articles: Targeted Expression of Tetanus Toxin; Germ-line Transformants Spreading Out to Many Insect Species; Genes Mediating Sex-Specific Behaviors in Drosophila; and Evolutionary Analyses of Genes and Their Functional Implications.
Publisher Summary 2
Advances in Geneticsincreases its focus on modern human genetics and its relation to medicine with the merger of this long-standing serial with Molecular Genetic Medicine. This merger affirms the Academic Press commitment to publish important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.
Genetics, the science of heredity, lies at the heart of biology, and many diseases are impacted by an individuals genetic make-up. The field of genetics is rapidly evolving and new medical break-throughs are occurring as a result of advances in knowledge of genetics. Advances in Genetics continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. This volume of Advances in Geneticscontains the following articles: Targeted Expression of Tetanus Toxin; Germ-line Transformants Spreading Out to Many Insect Species; Genes Mediating Sex-Specific Behaviors in Drosophila; and Evolutionary Analyses of Genes and Their Functional Implications.
目录
Contributors p. vii
1 Rapidly Evolving Rab GTPase Paralogs and Reproductive Isolation in Drosophila Pierre Hutter p. 1
I Introduction p. 2
II Experimental Approaches p. 5
III Influences of Rab9D on Viability of Hybrids Between D. melanogaster and Its Sibling Species p. 5
IV Predictions of Functions for 6paRAB9 Proteins p. 14
V General Considerations p. 16
References p. 20
2 The Neurospora crassa Circadian Clock Christian Heintzen and Yi Liu p. 25
I Introduction p. 26
II Neurospora as a Circadian Model System p. 27
III The Molecular Machinery of the Neurospora Circadian Oscillator p. 28
IV Temporal Input from the Environment p. 42
V Temporal Output from the Oscillator p. 54
VI FRQ-Less Oscillators p. 56
VII Conclusions p. 58
References p. 59
3 Involvement of Homologous Recombination in Carcinogenesis Ramune Reliene and Alexander J. R. Bishop and Robert H. Schiestl p. 67
I Introduction p. 68
II HR Involvement in DNA Repair p. 69
III HR and Carcinogenesis p. 71
IV Other Diseases Attributable to HR p. 75
V Carcinogen-Induced HR in Experimental Systems p. 76
VI Summary p. 79
References p. 80
4 Mutational Analysis of the Ribosome Kathleen L. Triman p. 89
I Introduction p. 90
II Mutational Analysis of 16S rRNA Structure and Function p. 91
III Mutational Analysis of 23S rRNA Structure and Function p. 97
IV Mutational Analysis of Ribosomal Protein Structure and Function p. 103
V Mutational Analysis of Ribosomal Factor Structure and Function p. 106
VI Concluding Remarks p. 108
References p. 109
5 Application of Genomics to Molecular Breeding of Wheat and Barley Rajeev K. Varshney and Peter Langridge and Andreas Graner p. 121
I Introduction p. 122
II Molecular Markers and Marker-Assisted Breeding p. 123
III Genomic Resources and Approaches p. 131
IV Comparative Genomics p. 137
V Exploitation of Natural Variation and Allelic Diversity p. 138
VI Concluding Remarks p. 143
References p. 144
Index p. 157
1 Rapidly Evolving Rab GTPase Paralogs and Reproductive Isolation in Drosophila Pierre Hutter p. 1
I Introduction p. 2
II Experimental Approaches p. 5
III Influences of Rab9D on Viability of Hybrids Between D. melanogaster and Its Sibling Species p. 5
IV Predictions of Functions for 6paRAB9 Proteins p. 14
V General Considerations p. 16
References p. 20
2 The Neurospora crassa Circadian Clock Christian Heintzen and Yi Liu p. 25
I Introduction p. 26
II Neurospora as a Circadian Model System p. 27
III The Molecular Machinery of the Neurospora Circadian Oscillator p. 28
IV Temporal Input from the Environment p. 42
V Temporal Output from the Oscillator p. 54
VI FRQ-Less Oscillators p. 56
VII Conclusions p. 58
References p. 59
3 Involvement of Homologous Recombination in Carcinogenesis Ramune Reliene and Alexander J. R. Bishop and Robert H. Schiestl p. 67
I Introduction p. 68
II HR Involvement in DNA Repair p. 69
III HR and Carcinogenesis p. 71
IV Other Diseases Attributable to HR p. 75
V Carcinogen-Induced HR in Experimental Systems p. 76
VI Summary p. 79
References p. 80
4 Mutational Analysis of the Ribosome Kathleen L. Triman p. 89
I Introduction p. 90
II Mutational Analysis of 16S rRNA Structure and Function p. 91
III Mutational Analysis of 23S rRNA Structure and Function p. 97
IV Mutational Analysis of Ribosomal Protein Structure and Function p. 103
V Mutational Analysis of Ribosomal Factor Structure and Function p. 106
VI Concluding Remarks p. 108
References p. 109
5 Application of Genomics to Molecular Breeding of Wheat and Barley Rajeev K. Varshney and Peter Langridge and Andreas Graner p. 121
I Introduction p. 122
II Molecular Markers and Marker-Assisted Breeding p. 123
III Genomic Resources and Approaches p. 131
IV Comparative Genomics p. 137
V Exploitation of Natural Variation and Allelic Diversity p. 138
VI Concluding Remarks p. 143
References p. 144
Index p. 157
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