简介
Summary:
Publisher Summary 1
Choi (nutrition science and policy, USDA Human Nutrition Research Center on Aging, Tufts U.) and Friso (internal medicine, U. of Verona School of Medicine, Italy) assemble 10 chapters that examine how nutrients alter physiologic and pathologic processes in the human body through epigenetic changes without affecting the DNA sequence. Scientists in medicine and nutrition from the US and UK explore the interrelationships between nutrition and epigenetic phenomena, including DNA methylation, histone modifications, and chromatin remodeling; the role of epigenetics in embryonic development, aging, inflammation, and the development of cancer; and how nutrients affect and modulate these physiologic and pathologic processes. Annotation 漏2009 Book News, Inc., Portland, OR (booknews.com)
目录
Preface p. vii
The Editors p. ix
Contributors p. xi
Chapter 1 Introduction Simonetta Friso and Sang-Woon Choi p. 1
Chapter 2 Methylation on the nucleosome Da Jia and Xiaodong Cheng p. 7
Chapter 3 Mammalian DNA methyltransferases Michael J. Boland and Judith K. Christman p. 37
Chapter 4 Chromatin remodeling and histone modifications Gavin R. Schnitzler p. 67
Chapter 5 Nutrients and DNA methylation Sang-Woon Choi and Roberto Corrocher and Simonetta Friso p. 105
Chapter 6 Nutrients, histone modifications, and chromatin remodeling in chronic inflammation Barbara Delage and Roderick H. Dashwood p. 127
Chapter 7 Nutrients, epigenetics, and embryonic development Craig A. Cooney p. 155
Chapter 8 Nutrition, epigenetics, and aging John C. Mathers and Dianne Ford p. 175
Chapter 9 Nutrition, epigenetics, and cancer Sharon A. Ross p. 207
Chapter 10 Conclusions and future perspectives Sang-Woon Choi and Simonetta Friso p. 229
Index p. 233
The Editors p. ix
Contributors p. xi
Chapter 1 Introduction Simonetta Friso and Sang-Woon Choi p. 1
Chapter 2 Methylation on the nucleosome Da Jia and Xiaodong Cheng p. 7
Chapter 3 Mammalian DNA methyltransferases Michael J. Boland and Judith K. Christman p. 37
Chapter 4 Chromatin remodeling and histone modifications Gavin R. Schnitzler p. 67
Chapter 5 Nutrients and DNA methylation Sang-Woon Choi and Roberto Corrocher and Simonetta Friso p. 105
Chapter 6 Nutrients, histone modifications, and chromatin remodeling in chronic inflammation Barbara Delage and Roderick H. Dashwood p. 127
Chapter 7 Nutrients, epigenetics, and embryonic development Craig A. Cooney p. 155
Chapter 8 Nutrition, epigenetics, and aging John C. Mathers and Dianne Ford p. 175
Chapter 9 Nutrition, epigenetics, and cancer Sharon A. Ross p. 207
Chapter 10 Conclusions and future perspectives Sang-Woon Choi and Simonetta Friso p. 229
Index p. 233
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