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Publisher Summary 1
The second edition (1999) is cited in Brandon/Hill ; the most evident change of the third edition of this revered text is the addition of "Thomas" to the title, in honor of Nobel Laureate E. Donnall Thomas (emeritus, U. of Washington School of Medicine), the pioneer in the field. Aside from chapter revisions throughout, ten new chapters cover such topics as stem cell expansion; the theory and application of non-myeloablative regimens prior to allogeneic hematopoietic cell transplantation; and the experimental basis for transplantation for autoimmune diseases, long-term complications, and other conditions. The initial section, on the scientific basis for hematopoietic cell transplantation, contains 32 chapters on such topics as molecular aspects of stem cell renewal, genetic manipulation of hematopoietic stem cells, pharmacologic purging of bone marrow, and mechanisms of tolerance. In all, 110 chapters are grouped in eight sections on patient-related issues, sources of hematopoietic cells for human transplant, complications and their management, allogeneic and autologous transplantation for acquired diseases, allogeneic transplantation for inherited disease, and a single chapter on the future of the field. The contributors are mainly from the US. Annotation 漏2004 Book News, Inc., Portland, OR (booknews.com)
Publisher Summary 2
NEW- the leading book in its field now fully updated and revised!
Click here to access two FREE sample chapters!
An Essential resource for all hematologists, oncologists, pathologists, pediatricians, immunologists and all others interested in this dynamic area of medicine!
Why you should buy this book....
Extensive coverage of subject area - from the scientific basis to the view of the future
Includes all experimental research and clinical application
Combined the knowledge and expertise of over 170 international specialists
Clear structure and layout
Over 500 illustrations, including a colour plate section
Why buy the NEW edition......
New and fully revised to reflect the latest developments in this fast moving field
10 new chapters, covering some of the latest developments - see below for the complete tables of content
目录
Contributors p. ix
Preface to the First Edition p. xvi
Preface to the Second Edition p. xvii
Preface to the Third Edition p. xviii
Tribute p. xix
List of Abbreviations p. xxi
Section 1 Scientific Basis for Hematopoietic Cell Transplantation
1 A History of Bone Marrow Transplantation E. Donnall Thomas p. 3
2 Uses and Growth of Hematopoietic Cell Transplantation Mary M. Horowitz p. 9
3 Overview of Hematopoietic Cell Transplantation Immunology Paul J. Martin p. 16
4 Histocompatibility Eric Mickelson and Effie W. Petersdorf p. 31
5 Functional Evolution of the Major Histocompatibility Complex Lakshmi K. Gaur p. 43
6 The Hematopoietic Microenvironment Claudio Brunstein and Catherine M. Verfaillie p. 53
7 Molecular Aspects of Stem Cell Renewal Peter M. Lansdorp p. 62
8 Biology of Hematopoietic Stem and Progenitor Cells Markus G. Manz and Koichi Akashi and Irving L. Weissman p. 69
9 Expansion of Hematopoietic Stem Cells Colleen Delaney and Robert Andrews and Irwin Bernstein p. 96
10 Methods for Gene Transfer: Genetic Manipulation of Hematopoietic Stem Cells Thomas Moritz and David A. Williams p. 107
11 Clinical Trials of Gene Marking and Gene Therapy Using Hematopoietic Stem Cells Donald B. Kohn and Gay M. Crooks p. 118
12 Pharmacological Basis for High-Dose Chemotherapy James H. Doroshow and Timothy Synold p. 130
13 Preparative Regimens and Modification of Regimen-Related Toxicities William I. Bensinger and Ricardo Spielberger p. 158
14 Radiotherapeutic Principles of Hematopoietic Cell Transplantation Brenda Shank and Richard T. Hoppe p. 178
15 Radioimmunotherapy and Hematopoietic Cell Transplantation Dana C. Matthews and Frederick R. Appelbaum p. 198
16 Pharmacology and the Use of Immunosuppressive Agents after Hematopoietic Cell Transplantation Nelson J. Chao p. 209
17 T-Cell Depletion to Prevent Graft-vs.-Host Disease Robert J. Soiffer p. 221
18 Documentation of Engraftment and Characterization of Chimerism Following Hematopoietic Cell Transplantation Eileen Bryant and Paul J. Martin p. 234
19 Antibody Mediated Purging John G. Gribben p. 244
20 Pharmacologic Purging of Bone Marrow O. Michael Colvin p. 254
21 Molecular Inhibition of Gene Expression in Hematopoietic Cells Joanna B. Opalinska and Alan M. Gewirtz p. 258
22 The Detection and Significance of Minimal Residual Disease Jerald P. Radich and Marilyn L. Slovak p. 272
23 Pathology of Hematopoietic Cell Transplantation George E. Sale and Howard M. Shulman and Robert C. Hackman p. 286
24 Mechanisms of Tolerance Megan Sykes p. 300
25 The Experimental Basis for Hematopoietic Cell Transplantation for Autoimmune Diseases Judith A. Shizuru p. 324
26 Murine Models for Graft-vs.-Host Disease Robert Korngold and Thea M. Friedman p. 344
27 The Pathophysiology of Graft-vs.-Host Disease James L.M. Ferrara and Joseph Antin p. 353
28 Graft-versus-Tumor Responses Alexander Fefer p. 369
29 Adoptive Immunotherapy with Antigen-Specific T Cells Stanley R. Riddell and Philip D. Greenberg p. 380
30 Autologous Graft-vs.-Host Disease Allan D. Hess and Richard J. Jones p. 405
31 Biostatistical Methods in Hematopoietic Cell Transplantation Joyce C. Niland p. 414
32 Outcomes Research in Hematopoietic Cell Transplantation Stephanie J. Lee p. 434
Section 2 Patient-Related Issues in Hematopoietic Cell Transplantation
33 The Evaluation and Counseling of Candidates for Hematopoietic Cell Transplantation Karl G. Blume and Michael D. Amylon p. 449
34 Clinical and Administrative Support for Hematopoietic Cell Transplant Programs Laura L. Adams and Angela A. Johns p. 463
35 Nursing Issues in Hematopoietic Cell Transplantation Rosemary C. Ford and Judy Campbell and Juanita Madison p. 469
36 The Patient's Perspective Susan K. Stewart p. 483
37 Ethical Issues in Hematopoietic Cell Transplantation David S. Snyder p. 488
38 Psychosocial Issues in Hematopoietic Cell Transplantation Michael A. Andrykowski and Richard P. McQuellon p. 497
39 Assessment of Quality of Life in Hematopoietic Cell Transplantation Recipients Karen Syrjala p. 507
40 Sexuality after Hematopoietic Cell Transplantation D. Kathryn Tierney p. 519
Section 3 Sources of Hematopoietic Cells for Human Transplant
41 Hematopoietic Cell Procurement, Processing and Transplantation: Regulation and Accreditation Phyllis I. Warkentin and Lewis Nick and Elizabeth J. Shpall p. 531
42 Hematopoietic Cell Donors Dennis L. Confer p. 538
43 Cord Blood Hematopoietic Cell Transplantation Hal E. Broxmeyer and Franklin O. Smith p. 550
44 In Utero Transplantation Alan W. Flake and Esmail D. Zanjani p. 565
45 Mobilization of Autologous Peripheral Blood Hematopoietic Cells for Support of High-Dose Cancer Therapy Judith Ng-Cashin and Thomas Shea p. 576
46 Peripheral Blood Hematopoietic Cells for Allogeneic Transplantation Norbert Schmitz p. 588
47 Cryopreservation of Hematopoietic Cells Scott D. Rowley p. 599
48 Recombinant Growth Factors after Hematopoietic Cell Transplantation Jurgen Finke and Roland Mertelsmann p. 613
49 Hematopoietic Cell Donor Registries Jeffrey W. Chell p. 624
Section 4 Complications and Their Management
50 Graft-vs.-Host Disease Keith M. Sullivan p. 635
51 Bacterial Infections John R. Wingard and Helen L. Leather p. 665
52 Fungal Infections after Hematopoietic Cell Transplantation Janice (Wes) M. Y. Brown p. 683
53 Cytomegalovirus Infection John A. Zaia p. 701
54 Herpes Simplex Virus Infections James I. Ito p. 727
55 Varicella-Zoster Virus Infections Ann M. Arvin p. 732
56 Epstein-Barr Virus Infection Richard F. Ambinder p. 749
57 Other Viral Infections after Hematopoietic Cell Transplantation Michael Boeckh p. 757
58 Gastrointestinal and Hepatic Complications Simone I. Strasser and George B. McDonald p. 769
59 Neurological Complications of Hematopoietic Cell Transplantation Harry Openshaw p. 811
60 Blood Group Incompatibilities and Hemolytic Complications of Hematopoietic Cell Transplantation Margaret R. O'Donnell p. 824
61 Principles of Transfusion Support before and after Hematopoietic Cell Transplantation Jeffrey McCullough p. 833
62 Immunological Reconstitution following Hematopoietic Cell Transplantation Robertson Parkman and Kenneth I. Weinberg p. 853
63 Vaccination of Hematopoietic Cell Transplant Recipients Clare A. Dykewicz p. 862
64 Pulmonary Complications after Hematopoietic Cell Transplantation David A. Horak p. 873
65 Nutritional Support of Hematopoietic Cell Recipients Sally Weisdorf-Schindele and Sarah Jane Schwarzenberg p. 883
66 Pain Management Jonathan R. Gavrin and F. Peter Buckley p. 894
67 Oral Complications Mark M. Schubert and Douglas E. Peterson and Michele E. Lloid p. 911
68 Growth and Development after Hematopoietic Cell Transplantation Jean E. Sanders p. 929
69 Delayed Complications after Hematopoietic Cell Transplantation Mary E.D. Flowers and H. Joachim Deeg p. 944
70 Secondary Malignancies after Hematopoietic Cell Transplantation Smita Bhatia and Ravi Bhatia p. 962
Section 5 Allogeneic Transplantation for Acquired Diseases
71 Allogeneic Hematopoietic Cell Transplantation for Aplastic Anemia George E. Georges and Rainer Storb p. 981
72 Allogeneic Transplantation for Paroxysmal Nocturnal Hemoglobinuria Robert P. Witherspoon p. 1002
73 Allogeneic Transplantation for Chronic Myeloid Leukemia Frederick R. Appelbaum p. 1007
74 Hematopoietic Cell Transplantation for Juvenile Myelomonocytic Leukemia Robert A. Krance p. 1018
75 Allogeneic Hematopoietic Cell Transplantation for Adult Patients with Acute Myeloid Leukemia Keith E. Stockerl-Goldstein and Karl G. Blume p. 1025
76 Allogeneic Transplantation for Acute Myeloid Leukemia in Children David A. Margolis and James T. Casper p. 1040
77 Allogeneic Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia in Adults Stephen J. Forman p. 1055
78 Allogeneic Transplantation for Acute Lymphoblastic Leukemia in Children Stella M. Davies and Norma K.C. Ramsay and John H. Kersey p. 1067
79 Allogeneic Transplantation for Myelodysplastic and Myeloproliferative Disorders Jeanne E. Anderson p. 1084
80 Allogeneic Hematopoietic Cell Transplantation for Multiple Myeloma David G. Maloney and Gosta Gahrton p. 1096
81 Allogeneic Transplantation for Lymphoma and Chronic Lymphocytic Leukemia Issa Khouri and Richard Champlin p. 1105
82 Hematopoietic Cell Transplantation from HLA Partially Matched Related Donors Claudio Anasetti and Andrea Velardi p. 1116
83 Hematopoietic Cell Transplantation from Unrelated Donors Effie W. Petersdorf p. 1132
84 Management of Relapse after Allogeneic Transplantation Robert H. Collins, Jr p. 1150
85 Nonmyeloablative Therapy and Hematopoietic Cell Transplantation for Hematologic Disorders Brenda M. Sandmaier and Rainer Storb p. 1164
86 Allogeneic Hematopoietic Cell Transplantation for Solid Tumors Richard W. Childs and Ramaprasad Srinivasan p. 1177
Section 6 Autologous Transplantation for Acquired Diseases
87 Autologous and Allogeneic Hematopoietic Cell Transplantation for Hodgkin's Disease Philip J. Bierman and Auayporn Nademanee p. 1191
88 Autologous Hematopoietic Cell Transplantation for Non-Hodgkin's Lymphoma Sandra J. Horning and James O. Armitage p. 1207
89 Autologous Hematopoietic Cell Transplantation for Acute Myeloid Leukemia Anthony S. Stein and Stephen J. Forman p. 1221
90 Autologous Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia Charles A. Linker p. 1238
91 Autologous Hematopoietic Cell Transplantation for Chronic Myeloid Leukemia Ravi Bhatia and Philip B. McGlave p. 1250
92 Autologous Hematopoietic Cell Transplantation for Multiple Myeloma Laurence Catley and Kenneth Anderson p. 1262
93 Autologous Hematopoietic Cell Transplantation for AL Amyloidosis Raymond L. Comenzo and Morie A. Gertz p. 1283
94 Hematopoietic Cell Transplantation for Breast Cancer Karen H. Antman p. 1298
95 Hematopoietic Cell Transplantation in Germ Cell Tumors Brandon Hayes-Lattin and Craig R. Nichols p. 1308
96 Hematopoietic Cell Transplantation in Ovarian Carcinoma Patrick J. Stiff p. 1320
97 Hematopoietic Cell Transplantation for Neuroblastoma Katherine K. Matthay p. 1333
98 Hematopoietic Cell Transplantation for Brain Tumors Ira J. Dunkel and Jonathan L. Finlay p. 1345
99 Hematopoietic Cell Transplantation for Pediatric Patients with Solid Tumors Allen R. Chen and Curt I. Civin p. 1354
100 AIDS and Hematopoietic Transplantation: HIV Infection, AIDS, Lymphoma and Gene Therapy John A. Zaia and J. Scott Cairns and John J. Rossi p. 1369
101 Hematopoietic Stem Cell Transplantation for Autoimmune Diseases Alan Tyndall and Alois Gratwohl p. 1385
102 Prevention and Therapy of Relapse following Autologous Hematopoietic Cell Transplantation Robert S. Negrin p. 1394
Section 7 Allogeneic Transplantation for Inherited Disease
103 Marrow Transplantation in Thalassemia Guido Lucarelli and Reginald A. Clift p. 1409
104 Hematopoietic Cell Transplantation for Sickle Cell Disease Mark C. Walters p. 1417
105 Hematopoietic Cell Transplantation for Immunodeficiency Diseases Trudy N. Small and Wilhelm Friedrich and Richard J. O'Reilly p. 1430
106 Hematopoietic Cell Transplantation for Osteopetrosis Peter F. Coccia p. 1443
107 Hematopoietic Cell Transplantation for Storage Diseases Charles Peters p. 1455
108 Hematopoietic Cell Transplantation for Macrophage and Granulocyte Disorders Rajni Agarwal p. 1471
109 Hematopoietic Cell Transplantation for Fanconi Anemia John E. Wagner and Margaret L. MacMillan and Arleen D. Auerbach p. 1483
Section 8 The Future
110 Hematopoietic Cell Transplantation in the 21st Century Ernest Beutler p. 1507
Section 9 Colorplates, facing page Robert C. Hackman p. 296
Index p. 1511
Preface to the First Edition p. xvi
Preface to the Second Edition p. xvii
Preface to the Third Edition p. xviii
Tribute p. xix
List of Abbreviations p. xxi
Section 1 Scientific Basis for Hematopoietic Cell Transplantation
1 A History of Bone Marrow Transplantation E. Donnall Thomas p. 3
2 Uses and Growth of Hematopoietic Cell Transplantation Mary M. Horowitz p. 9
3 Overview of Hematopoietic Cell Transplantation Immunology Paul J. Martin p. 16
4 Histocompatibility Eric Mickelson and Effie W. Petersdorf p. 31
5 Functional Evolution of the Major Histocompatibility Complex Lakshmi K. Gaur p. 43
6 The Hematopoietic Microenvironment Claudio Brunstein and Catherine M. Verfaillie p. 53
7 Molecular Aspects of Stem Cell Renewal Peter M. Lansdorp p. 62
8 Biology of Hematopoietic Stem and Progenitor Cells Markus G. Manz and Koichi Akashi and Irving L. Weissman p. 69
9 Expansion of Hematopoietic Stem Cells Colleen Delaney and Robert Andrews and Irwin Bernstein p. 96
10 Methods for Gene Transfer: Genetic Manipulation of Hematopoietic Stem Cells Thomas Moritz and David A. Williams p. 107
11 Clinical Trials of Gene Marking and Gene Therapy Using Hematopoietic Stem Cells Donald B. Kohn and Gay M. Crooks p. 118
12 Pharmacological Basis for High-Dose Chemotherapy James H. Doroshow and Timothy Synold p. 130
13 Preparative Regimens and Modification of Regimen-Related Toxicities William I. Bensinger and Ricardo Spielberger p. 158
14 Radiotherapeutic Principles of Hematopoietic Cell Transplantation Brenda Shank and Richard T. Hoppe p. 178
15 Radioimmunotherapy and Hematopoietic Cell Transplantation Dana C. Matthews and Frederick R. Appelbaum p. 198
16 Pharmacology and the Use of Immunosuppressive Agents after Hematopoietic Cell Transplantation Nelson J. Chao p. 209
17 T-Cell Depletion to Prevent Graft-vs.-Host Disease Robert J. Soiffer p. 221
18 Documentation of Engraftment and Characterization of Chimerism Following Hematopoietic Cell Transplantation Eileen Bryant and Paul J. Martin p. 234
19 Antibody Mediated Purging John G. Gribben p. 244
20 Pharmacologic Purging of Bone Marrow O. Michael Colvin p. 254
21 Molecular Inhibition of Gene Expression in Hematopoietic Cells Joanna B. Opalinska and Alan M. Gewirtz p. 258
22 The Detection and Significance of Minimal Residual Disease Jerald P. Radich and Marilyn L. Slovak p. 272
23 Pathology of Hematopoietic Cell Transplantation George E. Sale and Howard M. Shulman and Robert C. Hackman p. 286
24 Mechanisms of Tolerance Megan Sykes p. 300
25 The Experimental Basis for Hematopoietic Cell Transplantation for Autoimmune Diseases Judith A. Shizuru p. 324
26 Murine Models for Graft-vs.-Host Disease Robert Korngold and Thea M. Friedman p. 344
27 The Pathophysiology of Graft-vs.-Host Disease James L.M. Ferrara and Joseph Antin p. 353
28 Graft-versus-Tumor Responses Alexander Fefer p. 369
29 Adoptive Immunotherapy with Antigen-Specific T Cells Stanley R. Riddell and Philip D. Greenberg p. 380
30 Autologous Graft-vs.-Host Disease Allan D. Hess and Richard J. Jones p. 405
31 Biostatistical Methods in Hematopoietic Cell Transplantation Joyce C. Niland p. 414
32 Outcomes Research in Hematopoietic Cell Transplantation Stephanie J. Lee p. 434
Section 2 Patient-Related Issues in Hematopoietic Cell Transplantation
33 The Evaluation and Counseling of Candidates for Hematopoietic Cell Transplantation Karl G. Blume and Michael D. Amylon p. 449
34 Clinical and Administrative Support for Hematopoietic Cell Transplant Programs Laura L. Adams and Angela A. Johns p. 463
35 Nursing Issues in Hematopoietic Cell Transplantation Rosemary C. Ford and Judy Campbell and Juanita Madison p. 469
36 The Patient's Perspective Susan K. Stewart p. 483
37 Ethical Issues in Hematopoietic Cell Transplantation David S. Snyder p. 488
38 Psychosocial Issues in Hematopoietic Cell Transplantation Michael A. Andrykowski and Richard P. McQuellon p. 497
39 Assessment of Quality of Life in Hematopoietic Cell Transplantation Recipients Karen Syrjala p. 507
40 Sexuality after Hematopoietic Cell Transplantation D. Kathryn Tierney p. 519
Section 3 Sources of Hematopoietic Cells for Human Transplant
41 Hematopoietic Cell Procurement, Processing and Transplantation: Regulation and Accreditation Phyllis I. Warkentin and Lewis Nick and Elizabeth J. Shpall p. 531
42 Hematopoietic Cell Donors Dennis L. Confer p. 538
43 Cord Blood Hematopoietic Cell Transplantation Hal E. Broxmeyer and Franklin O. Smith p. 550
44 In Utero Transplantation Alan W. Flake and Esmail D. Zanjani p. 565
45 Mobilization of Autologous Peripheral Blood Hematopoietic Cells for Support of High-Dose Cancer Therapy Judith Ng-Cashin and Thomas Shea p. 576
46 Peripheral Blood Hematopoietic Cells for Allogeneic Transplantation Norbert Schmitz p. 588
47 Cryopreservation of Hematopoietic Cells Scott D. Rowley p. 599
48 Recombinant Growth Factors after Hematopoietic Cell Transplantation Jurgen Finke and Roland Mertelsmann p. 613
49 Hematopoietic Cell Donor Registries Jeffrey W. Chell p. 624
Section 4 Complications and Their Management
50 Graft-vs.-Host Disease Keith M. Sullivan p. 635
51 Bacterial Infections John R. Wingard and Helen L. Leather p. 665
52 Fungal Infections after Hematopoietic Cell Transplantation Janice (Wes) M. Y. Brown p. 683
53 Cytomegalovirus Infection John A. Zaia p. 701
54 Herpes Simplex Virus Infections James I. Ito p. 727
55 Varicella-Zoster Virus Infections Ann M. Arvin p. 732
56 Epstein-Barr Virus Infection Richard F. Ambinder p. 749
57 Other Viral Infections after Hematopoietic Cell Transplantation Michael Boeckh p. 757
58 Gastrointestinal and Hepatic Complications Simone I. Strasser and George B. McDonald p. 769
59 Neurological Complications of Hematopoietic Cell Transplantation Harry Openshaw p. 811
60 Blood Group Incompatibilities and Hemolytic Complications of Hematopoietic Cell Transplantation Margaret R. O'Donnell p. 824
61 Principles of Transfusion Support before and after Hematopoietic Cell Transplantation Jeffrey McCullough p. 833
62 Immunological Reconstitution following Hematopoietic Cell Transplantation Robertson Parkman and Kenneth I. Weinberg p. 853
63 Vaccination of Hematopoietic Cell Transplant Recipients Clare A. Dykewicz p. 862
64 Pulmonary Complications after Hematopoietic Cell Transplantation David A. Horak p. 873
65 Nutritional Support of Hematopoietic Cell Recipients Sally Weisdorf-Schindele and Sarah Jane Schwarzenberg p. 883
66 Pain Management Jonathan R. Gavrin and F. Peter Buckley p. 894
67 Oral Complications Mark M. Schubert and Douglas E. Peterson and Michele E. Lloid p. 911
68 Growth and Development after Hematopoietic Cell Transplantation Jean E. Sanders p. 929
69 Delayed Complications after Hematopoietic Cell Transplantation Mary E.D. Flowers and H. Joachim Deeg p. 944
70 Secondary Malignancies after Hematopoietic Cell Transplantation Smita Bhatia and Ravi Bhatia p. 962
Section 5 Allogeneic Transplantation for Acquired Diseases
71 Allogeneic Hematopoietic Cell Transplantation for Aplastic Anemia George E. Georges and Rainer Storb p. 981
72 Allogeneic Transplantation for Paroxysmal Nocturnal Hemoglobinuria Robert P. Witherspoon p. 1002
73 Allogeneic Transplantation for Chronic Myeloid Leukemia Frederick R. Appelbaum p. 1007
74 Hematopoietic Cell Transplantation for Juvenile Myelomonocytic Leukemia Robert A. Krance p. 1018
75 Allogeneic Hematopoietic Cell Transplantation for Adult Patients with Acute Myeloid Leukemia Keith E. Stockerl-Goldstein and Karl G. Blume p. 1025
76 Allogeneic Transplantation for Acute Myeloid Leukemia in Children David A. Margolis and James T. Casper p. 1040
77 Allogeneic Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia in Adults Stephen J. Forman p. 1055
78 Allogeneic Transplantation for Acute Lymphoblastic Leukemia in Children Stella M. Davies and Norma K.C. Ramsay and John H. Kersey p. 1067
79 Allogeneic Transplantation for Myelodysplastic and Myeloproliferative Disorders Jeanne E. Anderson p. 1084
80 Allogeneic Hematopoietic Cell Transplantation for Multiple Myeloma David G. Maloney and Gosta Gahrton p. 1096
81 Allogeneic Transplantation for Lymphoma and Chronic Lymphocytic Leukemia Issa Khouri and Richard Champlin p. 1105
82 Hematopoietic Cell Transplantation from HLA Partially Matched Related Donors Claudio Anasetti and Andrea Velardi p. 1116
83 Hematopoietic Cell Transplantation from Unrelated Donors Effie W. Petersdorf p. 1132
84 Management of Relapse after Allogeneic Transplantation Robert H. Collins, Jr p. 1150
85 Nonmyeloablative Therapy and Hematopoietic Cell Transplantation for Hematologic Disorders Brenda M. Sandmaier and Rainer Storb p. 1164
86 Allogeneic Hematopoietic Cell Transplantation for Solid Tumors Richard W. Childs and Ramaprasad Srinivasan p. 1177
Section 6 Autologous Transplantation for Acquired Diseases
87 Autologous and Allogeneic Hematopoietic Cell Transplantation for Hodgkin's Disease Philip J. Bierman and Auayporn Nademanee p. 1191
88 Autologous Hematopoietic Cell Transplantation for Non-Hodgkin's Lymphoma Sandra J. Horning and James O. Armitage p. 1207
89 Autologous Hematopoietic Cell Transplantation for Acute Myeloid Leukemia Anthony S. Stein and Stephen J. Forman p. 1221
90 Autologous Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia Charles A. Linker p. 1238
91 Autologous Hematopoietic Cell Transplantation for Chronic Myeloid Leukemia Ravi Bhatia and Philip B. McGlave p. 1250
92 Autologous Hematopoietic Cell Transplantation for Multiple Myeloma Laurence Catley and Kenneth Anderson p. 1262
93 Autologous Hematopoietic Cell Transplantation for AL Amyloidosis Raymond L. Comenzo and Morie A. Gertz p. 1283
94 Hematopoietic Cell Transplantation for Breast Cancer Karen H. Antman p. 1298
95 Hematopoietic Cell Transplantation in Germ Cell Tumors Brandon Hayes-Lattin and Craig R. Nichols p. 1308
96 Hematopoietic Cell Transplantation in Ovarian Carcinoma Patrick J. Stiff p. 1320
97 Hematopoietic Cell Transplantation for Neuroblastoma Katherine K. Matthay p. 1333
98 Hematopoietic Cell Transplantation for Brain Tumors Ira J. Dunkel and Jonathan L. Finlay p. 1345
99 Hematopoietic Cell Transplantation for Pediatric Patients with Solid Tumors Allen R. Chen and Curt I. Civin p. 1354
100 AIDS and Hematopoietic Transplantation: HIV Infection, AIDS, Lymphoma and Gene Therapy John A. Zaia and J. Scott Cairns and John J. Rossi p. 1369
101 Hematopoietic Stem Cell Transplantation for Autoimmune Diseases Alan Tyndall and Alois Gratwohl p. 1385
102 Prevention and Therapy of Relapse following Autologous Hematopoietic Cell Transplantation Robert S. Negrin p. 1394
Section 7 Allogeneic Transplantation for Inherited Disease
103 Marrow Transplantation in Thalassemia Guido Lucarelli and Reginald A. Clift p. 1409
104 Hematopoietic Cell Transplantation for Sickle Cell Disease Mark C. Walters p. 1417
105 Hematopoietic Cell Transplantation for Immunodeficiency Diseases Trudy N. Small and Wilhelm Friedrich and Richard J. O'Reilly p. 1430
106 Hematopoietic Cell Transplantation for Osteopetrosis Peter F. Coccia p. 1443
107 Hematopoietic Cell Transplantation for Storage Diseases Charles Peters p. 1455
108 Hematopoietic Cell Transplantation for Macrophage and Granulocyte Disorders Rajni Agarwal p. 1471
109 Hematopoietic Cell Transplantation for Fanconi Anemia John E. Wagner and Margaret L. MacMillan and Arleen D. Auerbach p. 1483
Section 8 The Future
110 Hematopoietic Cell Transplantation in the 21st Century Ernest Beutler p. 1507
Section 9 Colorplates, facing page Robert C. Hackman p. 296
Index p. 1511
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