Selected fluorination in organic and bioogranic chemistry ACS Symposium series 456

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作   者:John T.Welch

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ISBN:9780841219489

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简介

Contains the proceedings of a symposium in Boston, April 1990, which explored the use of organofluorine compounds to alter the molecular properties of biological systems for industrial or research purposes. Covering theory, the synthesis of compounds, and biological compounds, the 14 papers discuss such topics as bond energies in reactive intermediates, perfluorated alkenes and dienes, and stereocontrolled synthesis.

目录

Tentative
Effects of Selective Fluorination on Reactivity in Organic and Bioorganic Chemistry: Introduction
The Effect of Fluorination on Polyacetylene and the Role of Internal Hydrogen Bonds to Fluorine: Molecular Orbital Models
Systematics and Surprises in Bond Energies of Fluorinated Reactive Intermediates
New Oxidants Containing the O-F Moiety and Some of their Uses in Organic Chemistry
Perfluorinated-Alkenes and -Dienes in a Diverse Chemistry
Perfluoro-Enolate Chemistry: Selective Generation and Unique Reactions of Ketone F-Enolates
New Approaches to a-Fluoro and a,a-Difluoro Functionalized Esters
Terminal Fluoroolefins: Synthesis and Applications to Mechanism-Based Enzyme Inhibition
Fluorine-Substituted Neuroactive Amines
Aldolases in Synthesis of Fluorosugars
Renin Inhibitors: Fluorine-Containing, Transition-State Analogue Inserts
The Effect of Fluorine Atom on Stereocontrolled Synthesis with Chemical or Microbial Methods
Fluoroolefin Dipeptide Isosteres
The Influence of Fluoro Substituents on the Reactivity of Carboxylic Acids, Amides, and Peptides in Enzyme-Catalyzed Reactions

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Selected fluorination in organic and bioogranic chemistry ACS Symposium series 456
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