Essential cell biology / 2nd ed.

Chapter 1 Introduction to Cells p. 1
Panel 1-1 Light and electron microscopy p. 8
Panel 1-2 Cells: the principal features of animal, plant, and bacterial cells p. 25
How We Know: Life's common mechanisms p. 30
Chapter 2 Chemical Components of Cells p. 39
How We Know: What are macromolecules? p. 60
Panel 2-1 Chemical bonds and groups p. 66
Panel 2-2 The chemical properties of water p. 68
Panel 2-3 An outline of some of the types of sugars p. 70
Panel 2-4 Fatty acids and other lipids p. 72
Panel 2-5 The 20 amino acids found in proteins p. 74
Panel 2-6 A survey of the nucleotides p. 76
Panel 2-7 The principal types of weak noncovalent bonds p. 78
Chapter 3 Energy, Catalysis, and Biosynthesis p. 83
Panel 3-1 Free energy and biological reactions p. 96
How We Know: Using kinetics to model and manipulate metabolic pathways p. 103
Chapter 4 Protein Structure and Function p. 119
Panel 4-1 A few examples of some general protein functions p. 120
How We Know: Probing protein structure p. 129
Panel 4-2 Four different ways of depicting a small protein p. 132
Panel 4-3 Cell breakage and initial fractionation of cell extracts p. 160
Panel 4-4 Protein separation by chromatography p. 162
Panel 4-5 Protein separation by electrophoresis p. 163
Panel 4-6 Making and using antibodies p. 164
Chapter 5 DNA and Chromosomes p. 169
How We Know: Genes are made of DNA p. 172
Chapter 6 DNA Replication, Repair, and Recombination p. 195
How We Know: Finding replication origins p. 198
Chapter 7 From DNA to Protein: How Cells Read the Genome p. 229
How We Know: Cracking the genetic code p. 246
Chapter 8 Control of Gene Expression p. 267
How We Know: Gene regulation--the story of eve p. 282
Chapter 9 How Genes and Genomes Evolve p. 293
How We Know: Counting genes p. 314
Chapter 10 Manipulating Genes and Cells p. 323
How We Know: Sequencing the human genome p. 334
Chapter 11 Membrane Structure p. 365
How We Know: Measuring membrane flow p. 384
Chapter 12 Membrane Transport p. 389
How We Know: Squid reveal secrets of membrane excitability p. 414
Chapter 13 How Cells Obtain Energy from Food p. 427
Panel 13-1 Details of the 10 steps of glycolysis p. 432
How We Know: Unraveling the citric acid cycle p. 442
Panel 13-2 The complete citric acid cycle p. 450
Chapter 14 Energy Generation in Mitochondria and Chloroplasts p. 453
How We Know: How chemiosmotic coupling drives ATP synthesis p. 460
Panel 14-1 Redox potentials p. 471
Chapter 15 Intracellular Compartments and Transport p. 497
How We Know: Tracking protein and vesicle transport p. 520
Chapter 16 Cell Communication p. 533
How We Know: Untangling cell signaling pathways p. 561
Chapter 17 Cytoskeleton p. 573
How We Know: Pursuing motor proteins p. 586
Chapter 18 Cell-Cycle Control and Cell Death p. 611
How We Know: Discovery of cyclins and Cdks p. 618
Chapter 19 Cell Division p. 637
Panel 19-1 The principal stages of M phase in an animal cell p. 642
How We Know: Building the mitotic spindle p. 646
Chapter 20 Genetics, Meiosis, and the Molecular Basis of Heredity p. 659
How We Know: Reading genetic linkage maps p. 682
Panel 20-1 Some essentials of classical genetics p. 685
Chapter 21 Tissues and Cancer p. 697
Panel 21-1 The cell types and tissues from which higher plants are constructed p. 700
How We Know: Making sense of the genes that are critical for cancer p. 734
Answers to Questions p. A:1
Glossary p. G:1
Index p. I:1