Molecular biology of the cell / 5th ed.

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作   者:Bruce Alberts ... [et al.] ; with problems by John Wilson, Tim Hunt.

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ISBN:9780815341055

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简介

  For nearly a quarter century, Molecular Biology of the Cell has been the leading cell biology textbook. This tradition continues with the new Fifth Edition, which has been completely revised and updated to describe our current, rapidly advancing understanding of cell biology. To list but a few examples, a large amount of new material is presented on:   * Epigenetics   * Stem cells   * RNAi   * Comparative genomics   * The latest cancer therapies   * Apoptosis (now its own separate chapter)   * Cell cycle control and the mechanics of M phase (now integrated into one chapter)   The hallmark features of Molecular Biology of the Cell have been retained, such as its consistent and comprehensive art program, clear concept headings, and succinct section summaries. Additionally, in response to extensive feedback from readers, the Fifth Edition now includes several new features. It is now more portable. Chapters 1-20 are printed and Chapters 21-25, covering multicellular systems, are provided as pdf files on the free Media DVD-ROM which accompanies the book. And for the first time, Molecular Biology of the Cell now contains end-of-chapter questions. These problems, written by John Wilson and Tim Hunt, emphasize a quantitative approach and the art of reasoning from experiments, and they will help students review and extend their knowledge derived from reading the textbook. The Media DVD-ROM, which is packaged with every copy of the book, contains PowerPoint? presentations with all of the figures, tables, and micrographs from the text (available as JPEGs too). Also included is the Media Player, which plays over 125 movies—animations, videos, and molecular models—all with voice-over narration. A new reader-friendly feature is the integration of media codes throughout the text that link directly to relevant videos and animations.   By skillfully extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and thereby create a coherent framework through which readers may approach and enjoy this subject that is so central to all of biology.  

目录

Special Features
Detailed Contents
Acknowledgments
A Note to the Reader
Introduction to the Cell
Cells and Genomes p. 1
Cell Chemistry and Biosynthesis p. 45
Proteins p. 125
Basic Genetic Mechanisms
DNA, Chromosomes, and Genomes p. 195
DNA Replication, Repair, and Recombination p. 263
How Cells Read the Genome: From DNA to Protein p. 329
Control of Gene Expression p. 411
Methods
Manipulating Proteins, DNA, and RNA p. 501
Visualizing Cells p. 579
Internal Organization of the Cell
Membrane Structure p. 617
Membrane Transport of Small Molecules and the Electrical Properties of Membranes p. 651
Intracellular Compartments and Protein Sorting p. 695
Intracellular Vesicular Traffic p. 749
Energy Conversion: Mitochondria and Chloroplasts p. 813
Mechanisms of Cell Communication p. 879
The Cytoskeleton p. 965
The Cell Cycle p. 1053
Apoptosis p. 1115
Cells in Their Social Context
Cell Junctions, Cell Adhesion, and the Extracellular Matrix p. 1131
Cancer p. 1205
Sexual Reproduction: Meiosis, Germ Cells, and Fertilization p. 1269
Development of Multicellular Organisms p. 1305
Specialized Tissues, Stem Cells, and Tissue Renewal p. 1417
Pathogens, Infection, and Innate Immunity p. 1485
The Adaptive Immune System p. 1539
Glossary
Index
Tables: The Genetic Code, Amino Acids

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